Identification of essential outstanding questions for an adequate European laboratory response to Ebolavirus Zaire West Africa 2014

Chantal Reusken, Matthias Niedrig, Suzan Pas, Pedro Anda, Sylvain Baize, Remi Charrel, Antonino Di Caro, Christian Drosten, Maria Dolores Fernandez-Garcia, Leticia Franco, Stephan Gunther, Isabelle Leparc-Goffart, Byron Martina, Delphine Pannetier, Anna Papa, Maria Paz Sanchez-Seco, Olli Vapalahti, Marion Koopmans

Research output: Contribution to journalArticlepeer-review

Abstract

On August 8 2014, the World Health Organization (WHO) declared the outbreak of Ebola Virus Disease (EVD) evolving in West Africa since December 2013, a Public Health Emergency of International Concern (PHEIC). It is expected that the outbreak of Ebolavirus Disease (EVD) in West Africa will lead to increased testing of individuals in Europe for EVD. The severity of the situation in West Africa warranted a critical appraisal of the laboratory preparedness and response for EVD, with a focus on information needs for laboratories involved in diagnostics of rare viral diseases associated with the European Network for the Diagnostics of "Imported" Viral Diseases", ENIVD. Essential knowledge and knowledge gaps for an adequate laboratory response focusing on virus properties, infection kinetics, tests specifics and field performances were identified. An inventory of the laboratory capacity for EVD diagnostics among ENIVD laboratories was made.

Original languageEnglish
Pages (from-to)124-134
Number of pages11
JournalJournal of Clinical Virology
Volume62
DOIs
Publication statusPublished - Jan 1 2015

Keywords

  • Diagnostics
  • Ebola virus
  • Laboratory preparedness
  • Viral haemorrhagic fever

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases
  • Medicine(all)

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