Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

Fergus J. Couch, Karoline Kuchenbaecker, Kyriaki Michailidou, Gustavo A. Mendoza-Fandino, Silje Nord, Janna Lilyquist, Curtis Olswold, Emily Hallberg, Simona Agata, Habibul Ahsan, Kristiina Aittomäki, Christine B. Ambrosone, Irene L. Andrulis, Hoda Anton-Culver, Volker Arndt, Banu K. Arun, Brita Arver, Monica Barile, Rosa B. Barkardottir, Daniel Barrowdale & 229 others Lars Beckmann, Matthias W. Beckmann, Javier Benitez, Stephanie Blank, Carl Blomqvist, Natalia V. Bogdanova, Stig E. Bojesen, Manjeet K. Bolla, Bernardo Bonanni, Hiltrud Brauch, Hermann Brenner, Barbara Burwinkel, Saundra S. Buys, Trinidad Caldes, Maria A. Caligo, F. Canzian, Jane Carpenter, Jenny Chang-Claude, Stephen J. Chanock, Wendy K. Chung, Kathleen Claes, Angela Cox, Simon S. Cross, Julie Cunningham, Kamila Czene, Mary B. Daly, Francesca Damiola, Hatef Darabi, Miguel de la Hoya, Peter Devilee, Orland Diez, Yuan Chun Ding, Riccardo Dolcetti, Susan M. Domchek, Cecilia M. Dorfling, Isabel Dos-Santos-Silva, Martine Dumont, Alison Dunning, Diana Eccles, Hans Ehrencrona, Arif B. Ekici, H. Eliassen, Steve Ellis, Peter A. Fasching, Jonine D. Figueroa, Dieter Flesch-Janys, Asta Försti, Florentia Fostira, W. D. Foulkes, Tara M. Friebel, Eitan Friedman, D. Frost, Marike Gabrielson, Marilie Gammon, Patricia A. Ganz, Susan M. Gapstur, Judy E. Garber, Mia M. Gaudet, Simon A. Gayther, Anne Marie Gerdes, Maya Ghoussaini, Graham Giles, Gord Glendon, Andrew K. Godwin, Mark S. Goldberg, David Goldgar, Anna González-Neira, Mark H. Greene, Jacek Gronwald, Pascal Guenel, Marc J. Gunter, Lothar Haeberle, Christopher A. Haiman, Ute Hamann, Thomas v O Hansen, Steven Hart, Sue Healey, Tuomas Heikkinen, Brian E. Henderson, Josef Herzog, Frans B. Hogervorst, Antoinette Hollestelle, Maartje J. Hooning, R. Hoover, John Hopper, Keith Humphreys, David J. Hunter, Tomasz Huzarski, Evgeny N. Imyanitov, Claudine Isaacs, Anna Jakubowska, Paul A. James, Ramunas Janavicius, Uffe Birk Jensen, Esther M. John, Michael E. Jones, Maria Kabisch, Siddhartha Kar, Beth Y. Karlan, Sofia Khan, Kay Thee Khaw, Muhammad G. Kibriya, Julia A. Knight, Yon Dschun Ko, Irene Konstantopoulou, Veli Matti Kosma, Vessela Kristensen, A. Kwong, Yael Laitman, Diether Lambrechts, Conxi Lazaro, Eunjung Lee, Loic Le Marchand, Jenny Lester, Annika Lindblom, Noralane Lindor, Sara Lindström, Jianjun Liu, Jirong Long, Jan Lubinski, Phuong L. Mai, Enes Makalic, Kathleen E. Malone, Arto Mannermaa, Siranoush Manoukian, Sara Margolin, Frederik Marme, John W M Martens, Lesley McGuffog, Alfons Meindl, Austin Miller, Roger L. Milne, Penelope Miron, Marco Montagna, Sylvie Mazoyer, Anna Marie Mulligan, Taru A. Muranen, Katherine L. Nathanson, Susan L. Neuhausen, Heli Nevanlinna, Børge G. Nordestgaard, Robert L. Nussbaum, Kenneth Offit, Edith Olah, Olufunmilayo I. Olopade, Janet E. Olson, Ana Osorio, Sue K. Park, P. H M Peeters, Bernard Gilles Peissel, Paolo Peterlongo, Julian Peto, Catherine M. Phelan, Robert Pilarski, Bruce Poppe, Katri Pylkäs, Paolo Radice, Nazneen Rahman, Johanna Rantala, Christine Rappaport, Gad Rennert, Andrea Richardson, Mark E. Robson, Isabelle Romieu, Anja Rudolph, E. Rutgers, Maria José Sanchez, Regina Santella, Elinor J. Sawyer, Daniel Schmidt, Marjanka K. Schmidt, Rita K. Schmutzler, Fredrick Schumacher, Rodney J. Scott, Leigha Senter, Priyanka Sharma, Jacques Simard, Christian F. Singer, Olga M. Sinilnikova, Penny Soucy, Melissa Southey, Doris Steinemann, Marie Stenmark-Askmalm, Dominique Stoppa-Lyonnet, Anthony J. Swerdlow, Csilla I. Szabo, Rulla Tamimi, William J. Tapper, Manuel R. Teixeira, Soo Hwang Teo, Mary Beth Terry, Mads Thomassen, Deborah J. Thompson, Laima Tihomirova, Amanda E. Toland, Robert A E M Tollenaar, Ian Tomlinson, Thérèse Truong, Helen Tsimiklis, A. Teulé, Rosario Tumino, Nadine Tung, Clare Turnbull, Giski Ursin, Carolien H M Van Deurzen, Elizabeth J. van Rensburg, Raymonda Varon-Mateeva, Zhaoming Wang, Shan Wang-Gohrke, Elisabete Weiderpass, Jeffrey Weitzel, Alice S. Whittemore, H. Wildiers, Robert Winqvist, Xiaohong R. Yang, Drakoulis Yannoukakos, Song Yao, M. Pilar Zamora, Wei Zheng, Per Hall, Peter Kraft, Celine Vachon, Susan Slager, Georgia Chenevix-Trench, Paul D P Pharoah, Alvaro A N Monteiro, Montse Garcia-Closas, Douglas F. Easton, Antonis C. Antoniou

Research output: Contribution to journalArticle

Abstract

Common variants in 94 loci have been associated with breast cancer including 15 loci with genome-wide significant associations (P

Original languageEnglish
Article number11375
JournalNature Communications
Volume7
DOIs
Publication statusPublished - Apr 27 2016

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estrogens
loci
breast
Estrogen Receptors
Genes
cancer
Genome
Breast Neoplasms
magnetic permeability
genome

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Chemistry(all)
  • Physics and Astronomy(all)

Cite this

Couch, F. J., Kuchenbaecker, K., Michailidou, K., Mendoza-Fandino, G. A., Nord, S., Lilyquist, J., ... Antoniou, A. C. (2016). Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer. Nature Communications, 7, [11375]. https://doi.org/10.1038/ncomms11375

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer. / Couch, Fergus J.; Kuchenbaecker, Karoline; Michailidou, Kyriaki; Mendoza-Fandino, Gustavo A.; Nord, Silje; Lilyquist, Janna; Olswold, Curtis; Hallberg, Emily; Agata, Simona; Ahsan, Habibul; Aittomäki, Kristiina; Ambrosone, Christine B.; Andrulis, Irene L.; Anton-Culver, Hoda; Arndt, Volker; Arun, Banu K.; Arver, Brita; Barile, Monica; Barkardottir, Rosa B.; Barrowdale, Daniel; Beckmann, Lars; Beckmann, Matthias W.; Benitez, Javier; Blank, Stephanie; Blomqvist, Carl; Bogdanova, Natalia V.; Bojesen, Stig E.; Bolla, Manjeet K.; Bonanni, Bernardo; Brauch, Hiltrud; Brenner, Hermann; Burwinkel, Barbara; Buys, Saundra S.; Caldes, Trinidad; Caligo, Maria A.; Canzian, F.; Carpenter, Jane; Chang-Claude, Jenny; Chanock, Stephen J.; Chung, Wendy K.; Claes, Kathleen; Cox, Angela; Cross, Simon S.; Cunningham, Julie; Czene, Kamila; Daly, Mary B.; Damiola, Francesca; Darabi, Hatef; de la Hoya, Miguel; Devilee, Peter; Diez, Orland; Ding, Yuan Chun; Dolcetti, Riccardo; Domchek, Susan M.; Dorfling, Cecilia M.; Dos-Santos-Silva, Isabel; Dumont, Martine; Dunning, Alison; Eccles, Diana; Ehrencrona, Hans; Ekici, Arif B.; Eliassen, H.; Ellis, Steve; Fasching, Peter A.; Figueroa, Jonine D.; Flesch-Janys, Dieter; Försti, Asta; Fostira, Florentia; Foulkes, W. D.; Friebel, Tara M.; Friedman, Eitan; Frost, D.; Gabrielson, Marike; Gammon, Marilie; Ganz, Patricia A.; Gapstur, Susan M.; Garber, Judy E.; Gaudet, Mia M.; Gayther, Simon A.; Gerdes, Anne Marie; Ghoussaini, Maya; Giles, Graham; Glendon, Gord; Godwin, Andrew K.; Goldberg, Mark S.; Goldgar, David; González-Neira, Anna; Greene, Mark H.; Gronwald, Jacek; Guenel, Pascal; Gunter, Marc J.; Haeberle, Lothar; Haiman, Christopher A.; Hamann, Ute; Hansen, Thomas v O; Hart, Steven; Healey, Sue; Heikkinen, Tuomas; Henderson, Brian E.; Herzog, Josef; Hogervorst, Frans B.; Hollestelle, Antoinette; Hooning, Maartje J.; Hoover, R.; Hopper, John; Humphreys, Keith; Hunter, David J.; Huzarski, Tomasz; Imyanitov, Evgeny N.; Isaacs, Claudine; Jakubowska, Anna; James, Paul A.; Janavicius, Ramunas; Jensen, Uffe Birk; John, Esther M.; Jones, Michael E.; Kabisch, Maria; Kar, Siddhartha; Karlan, Beth Y.; Khan, Sofia; Khaw, Kay Thee; Kibriya, Muhammad G.; Knight, Julia A.; Ko, Yon Dschun; Konstantopoulou, Irene; Kosma, Veli Matti; Kristensen, Vessela; Kwong, A.; Laitman, Yael; Lambrechts, Diether; Lazaro, Conxi; Lee, Eunjung; Le Marchand, Loic; Lester, Jenny; Lindblom, Annika; Lindor, Noralane; Lindström, Sara; Liu, Jianjun; Long, Jirong; Lubinski, Jan; Mai, Phuong L.; Makalic, Enes; Malone, Kathleen E.; Mannermaa, Arto; Manoukian, Siranoush; Margolin, Sara; Marme, Frederik; Martens, John W M; McGuffog, Lesley; Meindl, Alfons; Miller, Austin; Milne, Roger L.; Miron, Penelope; Montagna, Marco; Mazoyer, Sylvie; Mulligan, Anna Marie; Muranen, Taru A.; Nathanson, Katherine L.; Neuhausen, Susan L.; Nevanlinna, Heli; Nordestgaard, Børge G.; Nussbaum, Robert L.; Offit, Kenneth; Olah, Edith; Olopade, Olufunmilayo I.; Olson, Janet E.; Osorio, Ana; Park, Sue K.; Peeters, P. H M; Peissel, Bernard Gilles; Peterlongo, Paolo; Peto, Julian; Phelan, Catherine M.; Pilarski, Robert; Poppe, Bruce; Pylkäs, Katri; Radice, Paolo; Rahman, Nazneen; Rantala, Johanna; Rappaport, Christine; Rennert, Gad; Richardson, Andrea; Robson, Mark E.; Romieu, Isabelle; Rudolph, Anja; Rutgers, E.; Sanchez, Maria José; Santella, Regina; Sawyer, Elinor J.; Schmidt, Daniel; Schmidt, Marjanka K.; Schmutzler, Rita K.; Schumacher, Fredrick; Scott, Rodney J.; Senter, Leigha; Sharma, Priyanka; Simard, Jacques; Singer, Christian F.; Sinilnikova, Olga M.; Soucy, Penny; Southey, Melissa; Steinemann, Doris; Stenmark-Askmalm, Marie; Stoppa-Lyonnet, Dominique; Swerdlow, Anthony J.; Szabo, Csilla I.; Tamimi, Rulla; Tapper, William J.; Teixeira, Manuel R.; Teo, Soo Hwang; Terry, Mary Beth; Thomassen, Mads; Thompson, Deborah J.; Tihomirova, Laima; Toland, Amanda E.; Tollenaar, Robert A E M; Tomlinson, Ian; Truong, Thérèse; Tsimiklis, Helen; Teulé, A.; Tumino, Rosario; Tung, Nadine; Turnbull, Clare; Ursin, Giski; Van Deurzen, Carolien H M; van Rensburg, Elizabeth J.; Varon-Mateeva, Raymonda; Wang, Zhaoming; Wang-Gohrke, Shan; Weiderpass, Elisabete; Weitzel, Jeffrey; Whittemore, Alice S.; Wildiers, H.; Winqvist, Robert; Yang, Xiaohong R.; Yannoukakos, Drakoulis; Yao, Song; Zamora, M. Pilar; Zheng, Wei; Hall, Per; Kraft, Peter; Vachon, Celine; Slager, Susan; Chenevix-Trench, Georgia; Pharoah, Paul D P; Monteiro, Alvaro A N; Garcia-Closas, Montse; Easton, Douglas F.; Antoniou, Antonis C.

In: Nature Communications, Vol. 7, 11375, 27.04.2016.

Research output: Contribution to journalArticle

Couch, FJ, Kuchenbaecker, K, Michailidou, K, Mendoza-Fandino, GA, Nord, S, Lilyquist, J, Olswold, C, Hallberg, E, Agata, S, Ahsan, H, Aittomäki, K, Ambrosone, CB, Andrulis, IL, Anton-Culver, H, Arndt, V, Arun, BK, Arver, B, Barile, M, Barkardottir, RB, Barrowdale, D, Beckmann, L, Beckmann, MW, Benitez, J, Blank, S, Blomqvist, C, Bogdanova, NV, Bojesen, SE, Bolla, MK, Bonanni, B, Brauch, H, Brenner, H, Burwinkel, B, Buys, SS, Caldes, T, Caligo, MA, Canzian, F, Carpenter, J, Chang-Claude, J, Chanock, SJ, Chung, WK, Claes, K, Cox, A, Cross, SS, Cunningham, J, Czene, K, Daly, MB, Damiola, F, Darabi, H, de la Hoya, M, Devilee, P, Diez, O, Ding, YC, Dolcetti, R, Domchek, SM, Dorfling, CM, Dos-Santos-Silva, I, Dumont, M, Dunning, A, Eccles, D, Ehrencrona, H, Ekici, AB, Eliassen, H, Ellis, S, Fasching, PA, Figueroa, JD, Flesch-Janys, D, Försti, A, Fostira, F, Foulkes, WD, Friebel, TM, Friedman, E, Frost, D, Gabrielson, M, Gammon, M, Ganz, PA, Gapstur, SM, Garber, JE, Gaudet, MM, Gayther, SA, Gerdes, AM, Ghoussaini, M, Giles, G, Glendon, G, Godwin, AK, Goldberg, MS, Goldgar, D, González-Neira, A, Greene, MH, Gronwald, J, Guenel, P, Gunter, MJ, Haeberle, L, Haiman, CA, Hamann, U, Hansen, TVO, Hart, S, Healey, S, Heikkinen, T, Henderson, BE, Herzog, J, Hogervorst, FB, Hollestelle, A, Hooning, MJ, Hoover, R, Hopper, J, Humphreys, K, Hunter, DJ, Huzarski, T, Imyanitov, EN, Isaacs, C, Jakubowska, A, James, PA, Janavicius, R, Jensen, UB, John, EM, Jones, ME, Kabisch, M, Kar, S, Karlan, BY, Khan, S, Khaw, KT, Kibriya, MG, Knight, JA, Ko, YD, Konstantopoulou, I, Kosma, VM, Kristensen, V, Kwong, A, Laitman, Y, Lambrechts, D, Lazaro, C, Lee, E, Le Marchand, L, Lester, J, Lindblom, A, Lindor, N, Lindström, S, Liu, J, Long, J, Lubinski, J, Mai, PL, Makalic, E, Malone, KE, Mannermaa, A, Manoukian, S, Margolin, S, Marme, F, Martens, JWM, McGuffog, L, Meindl, A, Miller, A, Milne, RL, Miron, P, Montagna, M, Mazoyer, S, Mulligan, AM, Muranen, TA, Nathanson, KL, Neuhausen, SL, Nevanlinna, H, Nordestgaard, BG, Nussbaum, RL, Offit, K, Olah, E, Olopade, OI, Olson, JE, Osorio, A, Park, SK, Peeters, PHM, Peissel, BG, Peterlongo, P, Peto, J, Phelan, CM, Pilarski, R, Poppe, B, Pylkäs, K, Radice, P, Rahman, N, Rantala, J, Rappaport, C, Rennert, G, Richardson, A, Robson, ME, Romieu, I, Rudolph, A, Rutgers, E, Sanchez, MJ, Santella, R, Sawyer, EJ, Schmidt, D, Schmidt, MK, Schmutzler, RK, Schumacher, F, Scott, RJ, Senter, L, Sharma, P, Simard, J, Singer, CF, Sinilnikova, OM, Soucy, P, Southey, M, Steinemann, D, Stenmark-Askmalm, M, Stoppa-Lyonnet, D, Swerdlow, AJ, Szabo, CI, Tamimi, R, Tapper, WJ, Teixeira, MR, Teo, SH, Terry, MB, Thomassen, M, Thompson, DJ, Tihomirova, L, Toland, AE, Tollenaar, RAEM, Tomlinson, I, Truong, T, Tsimiklis, H, Teulé, A, Tumino, R, Tung, N, Turnbull, C, Ursin, G, Van Deurzen, CHM, van Rensburg, EJ, Varon-Mateeva, R, Wang, Z, Wang-Gohrke, S, Weiderpass, E, Weitzel, J, Whittemore, AS, Wildiers, H, Winqvist, R, Yang, XR, Yannoukakos, D, Yao, S, Zamora, MP, Zheng, W, Hall, P, Kraft, P, Vachon, C, Slager, S, Chenevix-Trench, G, Pharoah, PDP, Monteiro, AAN, Garcia-Closas, M, Easton, DF & Antoniou, AC 2016, 'Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer', Nature Communications, vol. 7, 11375. https://doi.org/10.1038/ncomms11375
Couch FJ, Kuchenbaecker K, Michailidou K, Mendoza-Fandino GA, Nord S, Lilyquist J et al. Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer. Nature Communications. 2016 Apr 27;7. 11375. https://doi.org/10.1038/ncomms11375
Couch, Fergus J. ; Kuchenbaecker, Karoline ; Michailidou, Kyriaki ; Mendoza-Fandino, Gustavo A. ; Nord, Silje ; Lilyquist, Janna ; Olswold, Curtis ; Hallberg, Emily ; Agata, Simona ; Ahsan, Habibul ; Aittomäki, Kristiina ; Ambrosone, Christine B. ; Andrulis, Irene L. ; Anton-Culver, Hoda ; Arndt, Volker ; Arun, Banu K. ; Arver, Brita ; Barile, Monica ; Barkardottir, Rosa B. ; Barrowdale, Daniel ; Beckmann, Lars ; Beckmann, Matthias W. ; Benitez, Javier ; Blank, Stephanie ; Blomqvist, Carl ; Bogdanova, Natalia V. ; Bojesen, Stig E. ; Bolla, Manjeet K. ; Bonanni, Bernardo ; Brauch, Hiltrud ; Brenner, Hermann ; Burwinkel, Barbara ; Buys, Saundra S. ; Caldes, Trinidad ; Caligo, Maria A. ; Canzian, F. ; Carpenter, Jane ; Chang-Claude, Jenny ; Chanock, Stephen J. ; Chung, Wendy K. ; Claes, Kathleen ; Cox, Angela ; Cross, Simon S. ; Cunningham, Julie ; Czene, Kamila ; Daly, Mary B. ; Damiola, Francesca ; Darabi, Hatef ; de la Hoya, Miguel ; Devilee, Peter ; Diez, Orland ; Ding, Yuan Chun ; Dolcetti, Riccardo ; Domchek, Susan M. ; Dorfling, Cecilia M. ; Dos-Santos-Silva, Isabel ; Dumont, Martine ; Dunning, Alison ; Eccles, Diana ; Ehrencrona, Hans ; Ekici, Arif B. ; Eliassen, H. ; Ellis, Steve ; Fasching, Peter A. ; Figueroa, Jonine D. ; Flesch-Janys, Dieter ; Försti, Asta ; Fostira, Florentia ; Foulkes, W. D. ; Friebel, Tara M. ; Friedman, Eitan ; Frost, D. ; Gabrielson, Marike ; Gammon, Marilie ; Ganz, Patricia A. ; Gapstur, Susan M. ; Garber, Judy E. ; Gaudet, Mia M. ; Gayther, Simon A. ; Gerdes, Anne Marie ; Ghoussaini, Maya ; Giles, Graham ; Glendon, Gord ; Godwin, Andrew K. ; Goldberg, Mark S. ; Goldgar, David ; González-Neira, Anna ; Greene, Mark H. ; Gronwald, Jacek ; Guenel, Pascal ; Gunter, Marc J. ; Haeberle, Lothar ; Haiman, Christopher A. ; Hamann, Ute ; Hansen, Thomas v O ; Hart, Steven ; Healey, Sue ; Heikkinen, Tuomas ; Henderson, Brian E. ; Herzog, Josef ; Hogervorst, Frans B. ; Hollestelle, Antoinette ; Hooning, Maartje J. ; Hoover, R. ; Hopper, John ; Humphreys, Keith ; Hunter, David J. ; Huzarski, Tomasz ; Imyanitov, Evgeny N. ; Isaacs, Claudine ; Jakubowska, Anna ; James, Paul A. ; Janavicius, Ramunas ; Jensen, Uffe Birk ; John, Esther M. ; Jones, Michael E. ; Kabisch, Maria ; Kar, Siddhartha ; Karlan, Beth Y. ; Khan, Sofia ; Khaw, Kay Thee ; Kibriya, Muhammad G. ; Knight, Julia A. ; Ko, Yon Dschun ; Konstantopoulou, Irene ; Kosma, Veli Matti ; Kristensen, Vessela ; Kwong, A. ; Laitman, Yael ; Lambrechts, Diether ; Lazaro, Conxi ; Lee, Eunjung ; Le Marchand, Loic ; Lester, Jenny ; Lindblom, Annika ; Lindor, Noralane ; Lindström, Sara ; Liu, Jianjun ; Long, Jirong ; Lubinski, Jan ; Mai, Phuong L. ; Makalic, Enes ; Malone, Kathleen E. ; Mannermaa, Arto ; Manoukian, Siranoush ; Margolin, Sara ; Marme, Frederik ; Martens, John W M ; McGuffog, Lesley ; Meindl, Alfons ; Miller, Austin ; Milne, Roger L. ; Miron, Penelope ; Montagna, Marco ; Mazoyer, Sylvie ; Mulligan, Anna Marie ; Muranen, Taru A. ; Nathanson, Katherine L. ; Neuhausen, Susan L. ; Nevanlinna, Heli ; Nordestgaard, Børge G. ; Nussbaum, Robert L. ; Offit, Kenneth ; Olah, Edith ; Olopade, Olufunmilayo I. ; Olson, Janet E. ; Osorio, Ana ; Park, Sue K. ; Peeters, P. H M ; Peissel, Bernard Gilles ; Peterlongo, Paolo ; Peto, Julian ; Phelan, Catherine M. ; Pilarski, Robert ; Poppe, Bruce ; Pylkäs, Katri ; Radice, Paolo ; Rahman, Nazneen ; Rantala, Johanna ; Rappaport, Christine ; Rennert, Gad ; Richardson, Andrea ; Robson, Mark E. ; Romieu, Isabelle ; Rudolph, Anja ; Rutgers, E. ; Sanchez, Maria José ; Santella, Regina ; Sawyer, Elinor J. ; Schmidt, Daniel ; Schmidt, Marjanka K. ; Schmutzler, Rita K. ; Schumacher, Fredrick ; Scott, Rodney J. ; Senter, Leigha ; Sharma, Priyanka ; Simard, Jacques ; Singer, Christian F. ; Sinilnikova, Olga M. ; Soucy, Penny ; Southey, Melissa ; Steinemann, Doris ; Stenmark-Askmalm, Marie ; Stoppa-Lyonnet, Dominique ; Swerdlow, Anthony J. ; Szabo, Csilla I. ; Tamimi, Rulla ; Tapper, William J. ; Teixeira, Manuel R. ; Teo, Soo Hwang ; Terry, Mary Beth ; Thomassen, Mads ; Thompson, Deborah J. ; Tihomirova, Laima ; Toland, Amanda E. ; Tollenaar, Robert A E M ; Tomlinson, Ian ; Truong, Thérèse ; Tsimiklis, Helen ; Teulé, A. ; Tumino, Rosario ; Tung, Nadine ; Turnbull, Clare ; Ursin, Giski ; Van Deurzen, Carolien H M ; van Rensburg, Elizabeth J. ; Varon-Mateeva, Raymonda ; Wang, Zhaoming ; Wang-Gohrke, Shan ; Weiderpass, Elisabete ; Weitzel, Jeffrey ; Whittemore, Alice S. ; Wildiers, H. ; Winqvist, Robert ; Yang, Xiaohong R. ; Yannoukakos, Drakoulis ; Yao, Song ; Zamora, M. Pilar ; Zheng, Wei ; Hall, Per ; Kraft, Peter ; Vachon, Celine ; Slager, Susan ; Chenevix-Trench, Georgia ; Pharoah, Paul D P ; Monteiro, Alvaro A N ; Garcia-Closas, Montse ; Easton, Douglas F. ; Antoniou, Antonis C. / Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer. In: Nature Communications. 2016 ; Vol. 7.
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title = "Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer",
abstract = "Common variants in 94 loci have been associated with breast cancer including 15 loci with genome-wide significant associations (P",
author = "Couch, {Fergus J.} and Karoline Kuchenbaecker and Kyriaki Michailidou and Mendoza-Fandino, {Gustavo A.} and Silje Nord and Janna Lilyquist and Curtis Olswold and Emily Hallberg and Simona Agata and Habibul Ahsan and Kristiina Aittom{\"a}ki and Ambrosone, {Christine B.} and Andrulis, {Irene L.} and Hoda Anton-Culver and Volker Arndt and Arun, {Banu K.} and Brita Arver and Monica Barile and Barkardottir, {Rosa B.} and Daniel Barrowdale and Lars Beckmann and Beckmann, {Matthias W.} and Javier Benitez and Stephanie Blank and Carl Blomqvist and Bogdanova, {Natalia V.} and Bojesen, {Stig E.} and Bolla, {Manjeet K.} and Bernardo Bonanni and Hiltrud Brauch and Hermann Brenner and Barbara Burwinkel and Buys, {Saundra S.} and Trinidad Caldes and Caligo, {Maria A.} and F. Canzian and Jane Carpenter and Jenny Chang-Claude and Chanock, {Stephen J.} and Chung, {Wendy K.} and Kathleen Claes and Angela Cox and Cross, {Simon S.} and Julie Cunningham and Kamila Czene and Daly, {Mary B.} and Francesca Damiola and Hatef Darabi and {de la Hoya}, Miguel and Peter Devilee and Orland Diez and Ding, {Yuan Chun} and Riccardo Dolcetti and Domchek, {Susan M.} and Dorfling, {Cecilia M.} and Isabel Dos-Santos-Silva and Martine Dumont and Alison Dunning and Diana Eccles and Hans Ehrencrona and Ekici, {Arif B.} and H. Eliassen and Steve Ellis and Fasching, {Peter A.} and Figueroa, {Jonine D.} and Dieter Flesch-Janys and Asta F{\"o}rsti and Florentia Fostira and Foulkes, {W. D.} and Friebel, {Tara M.} and Eitan Friedman and D. 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Hoover and John Hopper and Keith Humphreys and Hunter, {David J.} and Tomasz Huzarski and Imyanitov, {Evgeny N.} and Claudine Isaacs and Anna Jakubowska and James, {Paul A.} and Ramunas Janavicius and Jensen, {Uffe Birk} and John, {Esther M.} and Jones, {Michael E.} and Maria Kabisch and Siddhartha Kar and Karlan, {Beth Y.} and Sofia Khan and Khaw, {Kay Thee} and Kibriya, {Muhammad G.} and Knight, {Julia A.} and Ko, {Yon Dschun} and Irene Konstantopoulou and Kosma, {Veli Matti} and Vessela Kristensen and A. Kwong and Yael Laitman and Diether Lambrechts and Conxi Lazaro and Eunjung Lee and {Le Marchand}, Loic and Jenny Lester and Annika Lindblom and Noralane Lindor and Sara Lindstr{\"o}m and Jianjun Liu and Jirong Long and Jan Lubinski and Mai, {Phuong L.} and Enes Makalic and Malone, {Kathleen E.} and Arto Mannermaa and Siranoush Manoukian and Sara Margolin and Frederik Marme and Martens, {John W M} and Lesley McGuffog and Alfons Meindl and Austin Miller and Milne, {Roger L.} and Penelope Miron and Marco Montagna and Sylvie Mazoyer and Mulligan, {Anna Marie} and Muranen, {Taru A.} and Nathanson, {Katherine L.} and Neuhausen, {Susan L.} and Heli Nevanlinna and Nordestgaard, {B{\o}rge G.} and Nussbaum, {Robert L.} and Kenneth Offit and Edith Olah and Olopade, {Olufunmilayo I.} and Olson, {Janet E.} and Ana Osorio and Park, {Sue K.} and Peeters, {P. H M} and Peissel, {Bernard Gilles} and Paolo Peterlongo and Julian Peto and Phelan, {Catherine M.} and Robert Pilarski and Bruce Poppe and Katri Pylk{\"a}s and Paolo Radice and Nazneen Rahman and Johanna Rantala and Christine Rappaport and Gad Rennert and Andrea Richardson and Robson, {Mark E.} and Isabelle Romieu and Anja Rudolph and E. Rutgers and Sanchez, {Maria Jos{\'e}} and Regina Santella and Sawyer, {Elinor J.} and Daniel Schmidt and Schmidt, {Marjanka K.} and Schmutzler, {Rita K.} and Fredrick Schumacher and Scott, {Rodney J.} and Leigha Senter and Priyanka Sharma and Jacques Simard and Singer, {Christian F.} and Sinilnikova, {Olga M.} and Penny Soucy and Melissa Southey and Doris Steinemann and Marie Stenmark-Askmalm and Dominique Stoppa-Lyonnet and Swerdlow, {Anthony J.} and Szabo, {Csilla I.} and Rulla Tamimi and Tapper, {William J.} and Teixeira, {Manuel R.} and Teo, {Soo Hwang} and Terry, {Mary Beth} and Mads Thomassen and Thompson, {Deborah J.} and Laima Tihomirova and Toland, {Amanda E.} and Tollenaar, {Robert A E M} and Ian Tomlinson and Th{\'e}r{\`e}se Truong and Helen Tsimiklis and A. Teul{\'e} and Rosario Tumino and Nadine Tung and Clare Turnbull and Giski Ursin and {Van Deurzen}, {Carolien H M} and {van Rensburg}, {Elizabeth J.} and Raymonda Varon-Mateeva and Zhaoming Wang and Shan Wang-Gohrke and Elisabete Weiderpass and Jeffrey Weitzel and Whittemore, {Alice S.} and H. Wildiers and Robert Winqvist and Yang, {Xiaohong R.} and Drakoulis Yannoukakos and Song Yao and Zamora, {M. Pilar} and Wei Zheng and Per Hall and Peter Kraft and Celine Vachon and Susan Slager and Georgia Chenevix-Trench and Pharoah, {Paul D P} and Monteiro, {Alvaro A N} and Montse Garcia-Closas and Easton, {Douglas F.} and Antoniou, {Antonis C.}",
year = "2016",
month = "4",
day = "27",
doi = "10.1038/ncomms11375",
language = "English",
volume = "7",
journal = "Nature Communications",
issn = "2041-1723",
publisher = "NLM (Medline)",

}

TY - JOUR

T1 - Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

AU - Couch, Fergus J.

AU - Kuchenbaecker, Karoline

AU - Michailidou, Kyriaki

AU - Mendoza-Fandino, Gustavo A.

AU - Nord, Silje

AU - Lilyquist, Janna

AU - Olswold, Curtis

AU - Hallberg, Emily

AU - Agata, Simona

AU - Ahsan, Habibul

AU - Aittomäki, Kristiina

AU - Ambrosone, Christine B.

AU - Andrulis, Irene L.

AU - Anton-Culver, Hoda

AU - Arndt, Volker

AU - Arun, Banu K.

AU - Arver, Brita

AU - Barile, Monica

AU - Barkardottir, Rosa B.

AU - Barrowdale, Daniel

AU - Beckmann, Lars

AU - Beckmann, Matthias W.

AU - Benitez, Javier

AU - Blank, Stephanie

AU - Blomqvist, Carl

AU - Bogdanova, Natalia V.

AU - Bojesen, Stig E.

AU - Bolla, Manjeet K.

AU - Bonanni, Bernardo

AU - Brauch, Hiltrud

AU - Brenner, Hermann

AU - Burwinkel, Barbara

AU - Buys, Saundra S.

AU - Caldes, Trinidad

AU - Caligo, Maria A.

AU - Canzian, F.

AU - Carpenter, Jane

AU - Chang-Claude, Jenny

AU - Chanock, Stephen J.

AU - Chung, Wendy K.

AU - Claes, Kathleen

AU - Cox, Angela

AU - Cross, Simon S.

AU - Cunningham, Julie

AU - Czene, Kamila

AU - Daly, Mary B.

AU - Damiola, Francesca

AU - Darabi, Hatef

AU - de la Hoya, Miguel

AU - Devilee, Peter

AU - Diez, Orland

AU - Ding, Yuan Chun

AU - Dolcetti, Riccardo

AU - Domchek, Susan M.

AU - Dorfling, Cecilia M.

AU - Dos-Santos-Silva, Isabel

AU - Dumont, Martine

AU - Dunning, Alison

AU - Eccles, Diana

AU - Ehrencrona, Hans

AU - Ekici, Arif B.

AU - Eliassen, H.

AU - Ellis, Steve

AU - Fasching, Peter A.

AU - Figueroa, Jonine D.

AU - Flesch-Janys, Dieter

AU - Försti, Asta

AU - Fostira, Florentia

AU - Foulkes, W. D.

AU - Friebel, Tara M.

AU - Friedman, Eitan

AU - Frost, D.

AU - Gabrielson, Marike

AU - Gammon, Marilie

AU - Ganz, Patricia A.

AU - Gapstur, Susan M.

AU - Garber, Judy E.

AU - Gaudet, Mia M.

AU - Gayther, Simon A.

AU - Gerdes, Anne Marie

AU - Ghoussaini, Maya

AU - Giles, Graham

AU - Glendon, Gord

AU - Godwin, Andrew K.

AU - Goldberg, Mark S.

AU - Goldgar, David

AU - González-Neira, Anna

AU - Greene, Mark H.

AU - Gronwald, Jacek

AU - Guenel, Pascal

AU - Gunter, Marc J.

AU - Haeberle, Lothar

AU - Haiman, Christopher A.

AU - Hamann, Ute

AU - Hansen, Thomas v O

AU - Hart, Steven

AU - Healey, Sue

AU - Heikkinen, Tuomas

AU - Henderson, Brian E.

AU - Herzog, Josef

AU - Hogervorst, Frans B.

AU - Hollestelle, Antoinette

AU - Hooning, Maartje J.

AU - Hoover, R.

AU - Hopper, John

AU - Humphreys, Keith

AU - Hunter, David J.

AU - Huzarski, Tomasz

AU - Imyanitov, Evgeny N.

AU - Isaacs, Claudine

AU - Jakubowska, Anna

AU - James, Paul A.

AU - Janavicius, Ramunas

AU - Jensen, Uffe Birk

AU - John, Esther M.

AU - Jones, Michael E.

AU - Kabisch, Maria

AU - Kar, Siddhartha

AU - Karlan, Beth Y.

AU - Khan, Sofia

AU - Khaw, Kay Thee

AU - Kibriya, Muhammad G.

AU - Knight, Julia A.

AU - Ko, Yon Dschun

AU - Konstantopoulou, Irene

AU - Kosma, Veli Matti

AU - Kristensen, Vessela

AU - Kwong, A.

AU - Laitman, Yael

AU - Lambrechts, Diether

AU - Lazaro, Conxi

AU - Lee, Eunjung

AU - Le Marchand, Loic

AU - Lester, Jenny

AU - Lindblom, Annika

AU - Lindor, Noralane

AU - Lindström, Sara

AU - Liu, Jianjun

AU - Long, Jirong

AU - Lubinski, Jan

AU - Mai, Phuong L.

AU - Makalic, Enes

AU - Malone, Kathleen E.

AU - Mannermaa, Arto

AU - Manoukian, Siranoush

AU - Margolin, Sara

AU - Marme, Frederik

AU - Martens, John W M

AU - McGuffog, Lesley

AU - Meindl, Alfons

AU - Miller, Austin

AU - Milne, Roger L.

AU - Miron, Penelope

AU - Montagna, Marco

AU - Mazoyer, Sylvie

AU - Mulligan, Anna Marie

AU - Muranen, Taru A.

AU - Nathanson, Katherine L.

AU - Neuhausen, Susan L.

AU - Nevanlinna, Heli

AU - Nordestgaard, Børge G.

AU - Nussbaum, Robert L.

AU - Offit, Kenneth

AU - Olah, Edith

AU - Olopade, Olufunmilayo I.

AU - Olson, Janet E.

AU - Osorio, Ana

AU - Park, Sue K.

AU - Peeters, P. H M

AU - Peissel, Bernard Gilles

AU - Peterlongo, Paolo

AU - Peto, Julian

AU - Phelan, Catherine M.

AU - Pilarski, Robert

AU - Poppe, Bruce

AU - Pylkäs, Katri

AU - Radice, Paolo

AU - Rahman, Nazneen

AU - Rantala, Johanna

AU - Rappaport, Christine

AU - Rennert, Gad

AU - Richardson, Andrea

AU - Robson, Mark E.

AU - Romieu, Isabelle

AU - Rudolph, Anja

AU - Rutgers, E.

AU - Sanchez, Maria José

AU - Santella, Regina

AU - Sawyer, Elinor J.

AU - Schmidt, Daniel

AU - Schmidt, Marjanka K.

AU - Schmutzler, Rita K.

AU - Schumacher, Fredrick

AU - Scott, Rodney J.

AU - Senter, Leigha

AU - Sharma, Priyanka

AU - Simard, Jacques

AU - Singer, Christian F.

AU - Sinilnikova, Olga M.

AU - Soucy, Penny

AU - Southey, Melissa

AU - Steinemann, Doris

AU - Stenmark-Askmalm, Marie

AU - Stoppa-Lyonnet, Dominique

AU - Swerdlow, Anthony J.

AU - Szabo, Csilla I.

AU - Tamimi, Rulla

AU - Tapper, William J.

AU - Teixeira, Manuel R.

AU - Teo, Soo Hwang

AU - Terry, Mary Beth

AU - Thomassen, Mads

AU - Thompson, Deborah J.

AU - Tihomirova, Laima

AU - Toland, Amanda E.

AU - Tollenaar, Robert A E M

AU - Tomlinson, Ian

AU - Truong, Thérèse

AU - Tsimiklis, Helen

AU - Teulé, A.

AU - Tumino, Rosario

AU - Tung, Nadine

AU - Turnbull, Clare

AU - Ursin, Giski

AU - Van Deurzen, Carolien H M

AU - van Rensburg, Elizabeth J.

AU - Varon-Mateeva, Raymonda

AU - Wang, Zhaoming

AU - Wang-Gohrke, Shan

AU - Weiderpass, Elisabete

AU - Weitzel, Jeffrey

AU - Whittemore, Alice S.

AU - Wildiers, H.

AU - Winqvist, Robert

AU - Yang, Xiaohong R.

AU - Yannoukakos, Drakoulis

AU - Yao, Song

AU - Zamora, M. Pilar

AU - Zheng, Wei

AU - Hall, Per

AU - Kraft, Peter

AU - Vachon, Celine

AU - Slager, Susan

AU - Chenevix-Trench, Georgia

AU - Pharoah, Paul D P

AU - Monteiro, Alvaro A N

AU - Garcia-Closas, Montse

AU - Easton, Douglas F.

AU - Antoniou, Antonis C.

PY - 2016/4/27

Y1 - 2016/4/27

N2 - Common variants in 94 loci have been associated with breast cancer including 15 loci with genome-wide significant associations (P

AB - Common variants in 94 loci have been associated with breast cancer including 15 loci with genome-wide significant associations (P

UR - http://www.scopus.com/inward/record.url?scp=84968760294&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84968760294&partnerID=8YFLogxK

U2 - 10.1038/ncomms11375

DO - 10.1038/ncomms11375

M3 - Article

VL - 7

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

M1 - 11375

ER -