Identification of Multiple Transcribed Sequences from the Spinal Muscular Atrophy Region on Human Chromosome 5

A. Pizzuti, A. Colosimo, A. Ratti, F. Capon, M. Gennarelli, V. Silani, C. Ghezzi, S. Locicero, G. Calabrese, G. Palka, G. Scarlato, G. Novelli, B. Dallapiccola

Research output: Contribution to journalArticle


We report the isolation and characterization of novel expressed sequences from the spinal muscular atrophy (SMA) region on human chromosome 5q13. Based on the sequence homology studies these cDNAs were grouped in four classes, one of which shows extensive homologies with the β-glucuronidase (BG) gene, differing in exon arrangement. The other cDNAs do not show any strong homology with known DNA sequences.

Original languageEnglish
Pages (from-to)294-301
Number of pages8
JournalBiochemical and Biophysical Research Communications
Issue number1
Publication statusPublished - Jan 5 1995


ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology
  • Biophysics
  • Biochemistry

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