Identification of N,1,4,4-tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl] amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (PHA-848125), a potent, orally available cyclin dependent kinase inhibitor

Maria Gabriella Brasca, Nadia Amboldi, Dario Ballinari, Alexander Cameron, Elena Casale, Giovanni Cervi, Maristella Colombo, Francesco Colotta, Valter Croci, Roberto D'Alessio, Francesco Fiorentini, Antonella Isacchi, Ciro Mercurio, Walter Moretti, Achille Panzeri, Wilma Pastori, Paolo Pevarello, Francesca Quartieri, Fulvia Roletto, Gabriella TraquandiPaola Vianello, Anna Vulpetti, Marina Ciomei

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