Identification of the central vestibular projections in man: a positron emission tomography activation study

Gabriella Bottini, Roberto Sterzi, Eraldo Paulesu, Giuseppe Vallar, Stefano F. Cappa, Francesco Erminio, Richard E. Passingham, Chris D. Frith, Richard S J Frackowiak

Research output: Contribution to journalArticle

283 Citations (Scopus)

Abstract

The cerebral representation of space depends on the integration of many different sensory inputs. The vestibular system provides one such input and its dysfunction can cause profound spatial disorientation. Using positron emission tomography (PET), we measured regional cerebral perfusion with various vestibular stimulations to map central vestibular projections and to investigate the cerebral basis of spatial disorientation. We showed that the temporoparietal cortex, the insula, the putamen, and the anterior cingulate cortex are the cerebral projections of the vestibular system in man and that the spatial disorientation caused by unilateral vestibular stimulation is associated with their asymmetric activation.

Original languageEnglish
Pages (from-to)164-169
Number of pages6
JournalExperimental Brain Research
Volume99
Issue number1
DOIs
Publication statusPublished - May 1994

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Putamen
Gyrus Cinguli
Positron-Emission Tomography
Perfusion

Keywords

  • Human
  • Positron emission tomography
  • Representation of space
  • Unilateral neglect
  • Vestibular system

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Identification of the central vestibular projections in man : a positron emission tomography activation study. / Bottini, Gabriella; Sterzi, Roberto; Paulesu, Eraldo; Vallar, Giuseppe; Cappa, Stefano F.; Erminio, Francesco; Passingham, Richard E.; Frith, Chris D.; Frackowiak, Richard S J.

In: Experimental Brain Research, Vol. 99, No. 1, 05.1994, p. 164-169.

Research output: Contribution to journalArticle

Bottini, G, Sterzi, R, Paulesu, E, Vallar, G, Cappa, SF, Erminio, F, Passingham, RE, Frith, CD & Frackowiak, RSJ 1994, 'Identification of the central vestibular projections in man: a positron emission tomography activation study', Experimental Brain Research, vol. 99, no. 1, pp. 164-169. https://doi.org/10.1007/BF00241421
Bottini, Gabriella ; Sterzi, Roberto ; Paulesu, Eraldo ; Vallar, Giuseppe ; Cappa, Stefano F. ; Erminio, Francesco ; Passingham, Richard E. ; Frith, Chris D. ; Frackowiak, Richard S J. / Identification of the central vestibular projections in man : a positron emission tomography activation study. In: Experimental Brain Research. 1994 ; Vol. 99, No. 1. pp. 164-169.
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