Abstract
Ferroxidase activity in human H-chain ferritin has been studied with the aid of site-directed mutagenesis. A site discovered by X-ray crystallography has now been identified as the ferroxidase centre. This centre is present only in H-chains and is located within the four-helix bundle of the chain fold.
Original language | English |
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Pages (from-to) | 207-210 |
Number of pages | 4 |
Journal | FEBS Letters |
Volume | 254 |
Issue number | 1-2 |
DOIs | |
Publication status | Published - Aug 28 1989 |
Keywords
- Enzyme activity
- Ferritin
- Ferritin, recombinant
- Ferroxidase
ASJC Scopus subject areas
- Biochemistry
- Biophysics
- Molecular Biology
- Cell Biology
- Genetics
- Structural Biology