Idiopathic central sleep apnoea syndrome treated with zolpidem

Daniela Grimaldi, Federica Provini, Roberto Vetrugno, Elena Antelmi, Vincenzo Donadio, Rocco Liguori, Giulia Pierangeli, Pietro Cortelli, Pasquale Montagna

Research output: Contribution to journalArticlepeer-review


We report the case of a 47-year-old man with idiopathic central sleep apnoeas recurring during wake-sleep transitions at night or at diurnal naps. Symptoms associated with central apnoeas were sudden awakening with shortness of breath, sleep fragmentation and daytime tiredness. Following the failure of CPAP and BiPAP, we treated the patient with zolpidem which reduced central apnoea events, improved sleep and eliminated the patient's nocturnal disturbing symptoms. Beneficial effects were still present after two years of treatment. Our case demonstrates that zolpidem may be beneficial in the long term treatment of idiopathic central sleep apnoea syndrome.

Original languageEnglish
Pages (from-to)355-357
Number of pages3
JournalNeurological Sciences
Issue number5
Publication statusPublished - Oct 2008


  • Idiopathic central sleep apnoea
  • Treatment
  • Zolpidem

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology


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