Idiopathic hypereosinophilic syndrome: A case evolving in B-lymphoblastic lymphoma

Maria Cristina Rapanotti, Roberta Caruso, Sergio Bernardini, Valentina Coletti, Francesco Lo-Coco, Giulio De Rossi

Research output: Contribution to journalArticlepeer-review


Idiopathic hypereosinophilic syndrome (HES) is a rare disease characterized by tissue involvement and organ dysfunction due to abnormal eosinophil proliferation. Evolution of HES into myeloid or T-cell malignancies has been frequently reported. Here, we describe a case of HES that preceded the occurrence of a high-grade B-lymphoblastic lymphoma in which clonal evolution has been demonstrated at the molecular level.

Original languageEnglish
Pages (from-to)975-979
Number of pages5
JournalLeukemia Research
Issue number8
Publication statusPublished - Aug 2005


  • B-cell clonality
  • Eosinophilic leukemia
  • Idiopathic hypereosinophilic syndrome

ASJC Scopus subject areas

  • Cancer Research
  • Hematology
  • Oncology


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