Idiopathic inflammatory polyradiculoneuropathy: Evaluation of clinical and laboratory data and therapeutic considerations

G. Valli, L. Ferini Strambi, E. Nobile Orazio, G. Scarlato

Research output: Contribution to journalArticle

Abstract

The clinical, immunological and neurophysiological data on 54 patients with idiopathic inflammatory polyradiculoneuropathy (IIP) are reviewed in order to reach a correct diagnostic and therapeutic approach. 49 of these patients presented acute and 5 recurrent IIP. Of the acute cases 10 patients had a severe course with paralysis of all limbs and respiratory insufficiency, and 3 died. An increase in CSF total proteins and impairment of nerve motor conduction velocities proved to be valuable tests for the diagnosis of IIP; these tests usually become more significant after 2 or 3 weeks of illness. Steroid treatment did not prove to be effective, while two patients with acute and progressive IIP, subjected to plasmapheresis, showed rapid and steady improvement. In these two patients the plasmapheresis was associated with azathioprine.

Original languageEnglish
Pages (from-to)19-26
Number of pages8
JournalItalian Journal of Neurological Sciences
Volume4
Issue number1
DOIs
Publication statusPublished - Apr 1983

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Keywords

  • CSF study
  • EMG study
  • idiopathic inflammatory polyradiculoneuropathy
  • plasmapheresis

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

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