Abstract
We report a case of idiopathic intracranial hypertension (IIH) (pseudotumor cerebri) following treatment with recombinant growth hormone (rhGH). A 9-year-old girl, treated for GH deficiency, developed bitemporal worsening headache, diplopia, intermittent exotropia and visual loss 3 months after starting rhGH. Ocular fundus examination revealed bilateral papilloedema and a MRI scan ruled out intracranial disease (including venous sinus thrombosis), leading to diagnosis of IIH. rhGH was discontinued and acetazolamide therapy was initiated up to 30 mg/kg/die dose without clinical improvement and with mild metabolic acidosis. We reduced acetazolamide to 20 mg/kg/die and added dexamethasone ev (0,4 mg/kg/die) with dramatic answer already after 1 day, then confirmed by fundus oculi and visual evocated potential. We suggest the use of corticosteroids in IIH when acetazolamide is inefficient or intolerable.
Translated title of the contribution | Idiopathic intracranial hypertension (pseudotumor cerebri) in a girl receiving growth hormone treatment |
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Original language | Italian |
Pages (from-to) | 460-461 |
Number of pages | 2 |
Journal | Medico e Bambino |
Volume | 26 |
Issue number | 7 |
Publication status | Published - Sep 30 2007 |
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health