Ipertensione endocranica idiopatica (pseudotumor cerebri) in una bambina in terapia con ormone della crescita

Translated title of the contribution: Idiopathic intracranial hypertension (pseudotumor cerebri) in a girl receiving growth hormone treatment

G. Tornese, F. Patarino, S. Pensiero, F. Parentin, E. Faleschini, G. Tonini, F. Marchetti

Research output: Contribution to journalArticlepeer-review

Abstract

We report a case of idiopathic intracranial hypertension (IIH) (pseudotumor cerebri) following treatment with recombinant growth hormone (rhGH). A 9-year-old girl, treated for GH deficiency, developed bitemporal worsening headache, diplopia, intermittent exotropia and visual loss 3 months after starting rhGH. Ocular fundus examination revealed bilateral papilloedema and a MRI scan ruled out intracranial disease (including venous sinus thrombosis), leading to diagnosis of IIH. rhGH was discontinued and acetazolamide therapy was initiated up to 30 mg/kg/die dose without clinical improvement and with mild metabolic acidosis. We reduced acetazolamide to 20 mg/kg/die and added dexamethasone ev (0,4 mg/kg/die) with dramatic answer already after 1 day, then confirmed by fundus oculi and visual evocated potential. We suggest the use of corticosteroids in IIH when acetazolamide is inefficient or intolerable.

Translated title of the contributionIdiopathic intracranial hypertension (pseudotumor cerebri) in a girl receiving growth hormone treatment
Original languageItalian
Pages (from-to)460-461
Number of pages2
JournalMedico e Bambino
Volume26
Issue number7
Publication statusPublished - Sep 30 2007

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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