IFCC Interim Guidelines on Biochemical/Hematological Monitoring of COVID-19 Patients

IFCC Taskforce on COVID-19

Research output: Contribution to journalReview articlepeer-review


Routine biochemical and hematological tests have been reported to be useful in the stratification and prognostication of pediatric and adult patients with diagnosed coronavirus disease (COVID-19), correlating with poor outcomes such as the need for mechanical ventilation or intensive care, progression to multisystem organ failure, and/or death. While these tests are already well established in most clinical laboratories, there is still debate regarding their clinical value in the management of COVID-19, particularly in pediatrics, as well as the value of composite clinical risk scores in COVID-19 prognostication. This document by the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Task Force on COVID-19 provides interim guidance on: (A) clinical indications for testing, (B) recommendations for test selection and interpretation, (C) considerations in test interpretation, and (D) current limitations of biochemical/hematological monitoring of COVID-19 patients. These evidence-based recommendations will provide practical guidance to clinical laboratories worldwide, underscoring the contribution of biochemical and hematological testing to our collective pandemic response.

Original languageEnglish
Pages (from-to)2009-2016
Number of pages8
JournalClinical Chemistry and Laboratory Medicine
Issue number12
Publication statusPublished - Nov 1 2020


  • biochemistry
  • COVID-19
  • hematology
  • SARS-CoV-2

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical


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