IFCC primary reference procedures for the measurement of catalytic activity concentrations of enzymes at 37 °C

Gerhard Schumann, Roberto Bonora, Ferruccio Ceriotti, Georges Férard, Carlo A. Ferrero, Paul F H Franck, F. Javier Gella, Wieland Hoelzel, Poul Jørgen Jørgensen, Takashi Kanno, Art Kessner, Rainer Klauke, Nina Kristianaen, Jean Marc Lessinger, Thomas P J Linsinger, Hideo Misaki, Mauro Panteghini, Jean Pauwels, Françoise Schiele, Heinz G. SchimmelGerhard Weidemann, Lothar Siekmann

Research output: Contribution to journalArticlepeer-review

Abstract

This paper is the fifth in a series dealing with reference procedures for the measurement of catalytic activity concentrations of enzymes at 37 °C and the certification of reference preparations. Other parts deal with: Part 1. The Concept of Reference Procedures for the Measurement of Catalytic Activity Concentrations of Enzymes; Part 2. Reference Procedure for the Measurement of Catalytic Concentration of Creatine Kinase; Part 3. Reference Procedure for the Measurement of Catalytic Concentration of Lactate Dehydrogenase; Part 4. Reference Procedure for the Measurement of Catalytic Concentration of Alanine Aminotransferase; Part 6. Reference Procedure for the Measurement of Catalytic Concentration of γ-Glutamyltransferase; Part 7. Certification of Four Reference Materials for the Determination of Enzymatic Activity of γ-Glutamyltransferase, Lactate Dehydrogenase, Alanine Aminotransferase and Creatine Kinase at 37°C. A document describing the determination of preliminary upper reference limits is also in preparation. The procedure described here is deduced from the previously described 30°C IFCC reference method (1). Differences are tabulated and commented on in Appendix 3.

Original languageEnglish
Pages (from-to)725-733
Number of pages9
JournalClinical Chemistry and Laboratory Medicine
Volume40
Issue number7
Publication statusPublished - 2002

Keywords

  • Aspartate aminotransferase
  • IFCC reference procedure
  • Preliminary upper reference limit

ASJC Scopus subject areas

  • Clinical Biochemistry

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