Abstract
Twenty-six patients with relapsed or refractory Hodgkin's disease (HD) were treated with an intensive salvage regimen combining ifosfamide (3000 mg/m2/d, days 1-4 through continuous intravenous infusion) and vinorelbine (25 mg/m2, i.v. days 1 and 5) with mesna uroprotection and G-CSF support. Courses were given at 3-week intervals. Ten patients achieved a complete and 10 patients a partial response, yielding an overall response rate of 77%. The main toxic effect was neutropenia and the combination was well tolerated.
Original language | English |
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Pages (from-to) | 533-535 |
Number of pages | 3 |
Journal | British Journal of Haematology |
Volume | 103 |
Issue number | 2 |
DOIs | |
Publication status | Published - 1998 |
Keywords
- Hodgkin's disease
- Ifosfamide
- Recurrent disease
- Salvage therapy
- Vinorelbine
ASJC Scopus subject areas
- Hematology