Abstract
In 8 children with selective IgA deficiency (serum IgA <5 mg/dl, secretory IgA <0.5 mg/dl in unstimulated saliva) immunofluorescent staining of intestinal biopsy specimens revealed the presence of IgA-containing plasma cells. This finding supports the hypothesis that in the intestinal mucosa of patients with IgA deficiency B lymphocytes undergo 'sterile' differentiation into IgA-containing plasma cells probably incapable of secreting the IgA synthesized.
Original language | English |
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Pages (from-to) | 173-175 |
Number of pages | 3 |
Journal | Journal of Clinical and Laboratory Immunology |
Volume | 9 |
Issue number | 3 |
Publication status | Published - 1982 |
ASJC Scopus subject areas
- Immunology