IgG and C3 receptors on polymorphonuclear leukocytes in phagocytosis. Role of C3-receptors in the attachment and ingestion phases

F. Capsoni, F. Caredda, P. Borzini, A. Lazzarin

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The role of IgG and complement (C3) receptors in the adhesion and ingestion phases of immune complexes by normal human polymorphonuclear leukocytes (PMN) were examined. The immune complexes were sheep red cells (E) sensitized with IgG (EA) or IgM antibodies plus complement (EAC'). Both types of receptor sites are involved in the adhesion phase. Moreover IgG receptors are primarily involved in the ingestion phase. Nevertheless even C3-receptors may be sufficient for complete phagocytosis. Even if EAC' adhesion was still high, C3-receptor specific phagocytosis decreased parallel with the amount of the complement used for EA19S sensibilization. The role of receptor sites on human PMN in adhesion and ingestion phases is discussed.

Original languageEnglish
Pages (from-to)442-448
Number of pages7
JournalBollettino dell'Istituto Sieroterapico Milanese
Volume56
Issue number5
Publication statusPublished - 1977

Fingerprint

IgG Receptors
Phagocytosis
Neutrophils
Eating
Antigen-Antibody Complex
Immunoglobulin G
Complement Receptors
Complement C3
Immunoglobulin M
Sheep
Antibodies

ASJC Scopus subject areas

  • Immunology

Cite this

IgG and C3 receptors on polymorphonuclear leukocytes in phagocytosis. Role of C3-receptors in the attachment and ingestion phases. / Capsoni, F.; Caredda, F.; Borzini, P.; Lazzarin, A.

In: Bollettino dell'Istituto Sieroterapico Milanese, Vol. 56, No. 5, 1977, p. 442-448.

Research output: Contribution to journalArticle

@article{4fb80ccd01394ed5a97e79631c4200c0,
title = "IgG and C3 receptors on polymorphonuclear leukocytes in phagocytosis. Role of C3-receptors in the attachment and ingestion phases",
abstract = "The role of IgG and complement (C3) receptors in the adhesion and ingestion phases of immune complexes by normal human polymorphonuclear leukocytes (PMN) were examined. The immune complexes were sheep red cells (E) sensitized with IgG (EA) or IgM antibodies plus complement (EAC'). Both types of receptor sites are involved in the adhesion phase. Moreover IgG receptors are primarily involved in the ingestion phase. Nevertheless even C3-receptors may be sufficient for complete phagocytosis. Even if EAC' adhesion was still high, C3-receptor specific phagocytosis decreased parallel with the amount of the complement used for EA19S sensibilization. The role of receptor sites on human PMN in adhesion and ingestion phases is discussed.",
author = "F. Capsoni and F. Caredda and P. Borzini and A. Lazzarin",
year = "1977",
language = "English",
volume = "56",
pages = "442--448",
journal = "Bollettino dell'Istituto Sieroterapico Milanese",
issn = "0021-2547",
number = "5",

}

TY - JOUR

T1 - IgG and C3 receptors on polymorphonuclear leukocytes in phagocytosis. Role of C3-receptors in the attachment and ingestion phases

AU - Capsoni, F.

AU - Caredda, F.

AU - Borzini, P.

AU - Lazzarin, A.

PY - 1977

Y1 - 1977

N2 - The role of IgG and complement (C3) receptors in the adhesion and ingestion phases of immune complexes by normal human polymorphonuclear leukocytes (PMN) were examined. The immune complexes were sheep red cells (E) sensitized with IgG (EA) or IgM antibodies plus complement (EAC'). Both types of receptor sites are involved in the adhesion phase. Moreover IgG receptors are primarily involved in the ingestion phase. Nevertheless even C3-receptors may be sufficient for complete phagocytosis. Even if EAC' adhesion was still high, C3-receptor specific phagocytosis decreased parallel with the amount of the complement used for EA19S sensibilization. The role of receptor sites on human PMN in adhesion and ingestion phases is discussed.

AB - The role of IgG and complement (C3) receptors in the adhesion and ingestion phases of immune complexes by normal human polymorphonuclear leukocytes (PMN) were examined. The immune complexes were sheep red cells (E) sensitized with IgG (EA) or IgM antibodies plus complement (EAC'). Both types of receptor sites are involved in the adhesion phase. Moreover IgG receptors are primarily involved in the ingestion phase. Nevertheless even C3-receptors may be sufficient for complete phagocytosis. Even if EAC' adhesion was still high, C3-receptor specific phagocytosis decreased parallel with the amount of the complement used for EA19S sensibilization. The role of receptor sites on human PMN in adhesion and ingestion phases is discussed.

UR - http://www.scopus.com/inward/record.url?scp=0017673233&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017673233&partnerID=8YFLogxK

M3 - Article

VL - 56

SP - 442

EP - 448

JO - Bollettino dell'Istituto Sieroterapico Milanese

JF - Bollettino dell'Istituto Sieroterapico Milanese

SN - 0021-2547

IS - 5

ER -