ILC3s: Rhythmic Keepers of Gut Integrity at Mealtime

Research output: Contribution to journalShort surveypeer-review

Abstract

Cyclically, during the day, increased permeability of the intestinal epithelial barrier, allowing nutrient uptake, must be compensated for, to achieve increased protection against potentially harmful components. Seillet et al. demonstrate that, upon food intake, enteric neuron-derived VIP promotes anticipatory mucosal immunity by inducing ILC3s to produce protective IL-22.

Original languageEnglish
JournalTrends in Immunology
DOIs
Publication statusAccepted/In press - Jan 1 2020

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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