Image Quality and Dose Reduction by Dual Source Computed Tomography Coronary Angiography: Protocol Comparison

Ernesto Forte, Serena Monti, Chiara Anna Parente, Lukas Beyer, Roberto De Rosa, Teresa Infante, Carlo Cavaliere, Filippo Cademartiri, Marco Salvatore, Christian Stroszczynski, Carlo Tedeschi

Research output: Contribution to journalArticlepeer-review


Purpose: To compare image quality and radiation dose among different protocols in patients who underwent a 128-slice dual source computed tomography coronary angiography (DSCT-CTCA). Methods: Ninety patients were retrospectively grouped according to heart rate (HR): 26 patients (group A) with stable HR ≤60 bpm were acquired using high pitch spiral mode (FLASH); 48 patients (group B) with irregular HR ≤60 bpm or stable HR between 60 and 70 bpm using step and shoot mode; and 16 patients (group C) with irregular HR >60 bpm or stable HR ≥70 bpm by retrospective electrocardiogram pulsing acquisition. Signal to noise ratio (SNR) and contrast to noise ratio (CNR) were measured for the main vascular structures. Moreover, the dose-length product and the effective dose were assessed. Results: Both SNR and CNR were higher in group A compared to group C (18.27 ± 0.32 vs 11.22 ± 0.50 and 16.75 ± 0.32 vs 10.17 ± 0.50; P =.001). The effective dose was lower in groups A and B (2.09 ± 1.27 mSv and 4.60 ± 2.78 mSv, respectively) compared to group C (9.61 ± 5.95 mSv) P <.0001. Conclusion: The correct selection of a low-dose, HR-matched CTCA scan protocol with a DSCT scanner provides substantial reduction of radiation exposure and better SNR and CNR.

Original languageEnglish
Issue number4
Publication statusPublished - Oct 1 2018


  • computed tomography coronary angiography
  • coronary artery disease
  • dual source computed tomography
  • image quality
  • radiation dose

ASJC Scopus subject areas

  • Toxicology
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis
  • Chemical Health and Safety


Dive into the research topics of 'Image Quality and Dose Reduction by Dual Source Computed Tomography Coronary Angiography: Protocol Comparison'. Together they form a unique fingerprint.

Cite this