Imaging in juvenile idiopathic arthritis (JIA): An update with particular emphasis on MRI

Maria Beatrice Damasio, L. Tanturri De Horatio, P. Boavida, K. Lambot-Juhan, K. Rosendahl, P. Tomà, L. S Ording Muller

Research output: Contribution to journalArticle

Abstract

Juvenile idiopathic arthritis (JIA) is a heterogeneous condition encompassing all forms of chronic arthritis of unknown origin and with onset before 16 years of age. During the last decade new, potent therapeutic agents have become available, underscoring the need for accurate monitoring of therapeutic response on both disease activity and structural damage to the joint. However, so far, treatment efficacy is based on clinical ground only, although clinical parameters are poor markers for disease activity and progression of structural damage. Not so for rheumatoid arthritis patients where the inclusion of radiographic assessment has been required by FDA to test the disease-modifying potential of new anti-rheumatic drugs. In imaging of children with JIA there has been a shift from traditional radiography towards newer techniques such as ultrasound and MRI, however without proper evaluation of their accuracy and validity. We here summarize present knowledge and discuss future challenges in imaging children with JIA.

Original languageEnglish
Pages (from-to)1015-1023
Number of pages9
JournalActa Radiologica
Volume54
Issue number9
DOIs
Publication statusPublished - Nov 2013

Keywords

  • Arthritis
  • Idiopathic
  • Juvenile
  • Magnetic resonance imaging (mri)
  • Pediatrics

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Medicine(all)

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