Imaging of a thymoma incidentally detected by C-11 choline PET/CT.

Federico Fallanca, Maria Picchio, Elena Giulia Spinapolice, Clara Ugolini, Agnese Proietti, Cristina Messa

Research output: Contribution to journalArticlepeer-review


The integrated modality positron emission tomography/computed tomography (PET/CT) with C-11 choline is an established diagnostic tool for restaging prostate cancer patients with a biochemical failure after primary treatment. Thymoma is a rare tumor originating in thymus epithelial cells, asymptomatic in one-third to one-half of patients, and often occurring in the fourth and fifth decades of life. In the present case, C-11 choline PET/CT was performed in a prostate cancer patient with a biochemical relapse, to restage the disease. In addition to the detection of local recurrent disease in prostatic fossa, an abnormal C-11 choline increased uptake in mediastinum was reported. The mediastinal finding was initially wrongly interpreted by clinicians as a lymph nodal metastasis from prostate cancer. However, histopathological analysis confirmed the presence of a thymoma. Although rare, thymoma has to be considered as differential diagnosis in case of mediastinal masses presenting C-11 choline PET/CT positive findings, to avoid inappropriate patient management.

Original languageEnglish
Pages (from-to)134-135
Number of pages2
JournalClinical Nuclear Medicine
Issue number2
Publication statusPublished - Feb 2011

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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