Imaging technologies in the differential diagnosis and follow-up of brown tumor in primary hyperparathyroidism: Case report and review of the literature

Davide Diacinti, Cristiana Cipriani, Federica Biamonte, Jessica Pepe, Luciano Colangelo, Endi Kripa, Antonio Iannacone, Martina Orlandi, Vito Guarnieri, Daniele Diacinti, Salvatore Minisola

Research output: Contribution to journalArticlepeer-review

Abstract

Brown tumors are osteolytic lesions associated with hyperparathyroidism (HPT). They may involve various skeletal segments, but rarely the cranio-facial bones. We report a case of a young boy with a swelling of the jaw secondary to a brown tumor presenting as the first manifestation of primary HPT (PHPT). He was found to have brown tumor located in the skull, as well. Different imaging technologies were employed for the diagnosis and follow-up after parathyroidectomy. We enclose a review of the literature on the employment of such imaging technologies in the differential diagnosis of osteolytic lesions. A multidisciplinary approach comprising clinical, laboratory and imaging findings is essential for the differential diagnosis of brown tumor in PHPT.

Original languageEnglish
Article number100745
JournalBone Reports
Volume14
DOIs
Publication statusPublished - Jun 2021

Keywords

  • Brown tumor
  • MRI
  • Parathyroid adenoma
  • Primary hyperparathyroidism

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Orthopedics and Sports Medicine

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