Immediate breast reconstruction with expander in pregnant breast cancer patients

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Background: Breast reconstruction after mastectomy is currently considered an essential component in managing breast cancer patients, particularly those diagnosed at a young age. However, no studies have been published on the feasibility of immediate breast reconstruction in patients diagnosed and operated during the course of gestation. Method: We retrospectively identified all breast cancer patients who were subjected to mastectomy and immediate breast reconstruction during pregnancy at the European Institute of Oncology between 2002 and 2012. Patient demographics, gestational age at surgery, tumor stage, adjuvant treatment, details of the surgical procedures, surgical outcomes and fetal outcomes were analyzed. Results: A total of 78 patients with breast cancer diagnosed during pregnancy were subjected to a surgical procedure during the course of gestation. Twenty-two patients had mastectomy; of whom 13 were subjected to immediate breast reconstruction. Twelve out of 13 patients had a two-stage procedure with tissue expander insertion. Median gestational age at surgery was 16 weeks. No major surgical complications were encountered. Only one patient elected to have an abortion, otherwise, no spontaneous abortions or pregnancy complications were reported. Median gestational age at delivery was 35 weeks (range: 32-40 weeks). No major congenital malformations were reported. At a median follow-up of 32months, all patients are alive with no long-term surgical complications. Conclusions: This is the first study of immediate breast reconstruction in pregnant breast cancer patients. Tissue expander insertion appears to ensure a short operative time, and does not seem to be associated with considerable morbidity to the patient or the fetus. Hence, it could be considered in the multidisciplinary management of women diagnosed with breast cancer during pregnancy.

Original languageEnglish
Pages (from-to)657-660
Number of pages4
JournalBreast
Volume22
Issue number5
DOIs
Publication statusPublished - Oct 2013

Fingerprint

Mammaplasty
Breast Neoplasms
Mastectomy
Pregnancy
Tissue Expansion Devices
Gestational Age
Pregnancy Complications
Spontaneous Abortion
Operative Time
Fetus
Demography
Morbidity

Keywords

  • Breast cancer
  • Immediate reconstruction
  • Mastectomy
  • Pregnancy

ASJC Scopus subject areas

  • Surgery

Cite this

@article{b8252f053aef4d538451c182f8f85a69,
title = "Immediate breast reconstruction with expander in pregnant breast cancer patients",
abstract = "Background: Breast reconstruction after mastectomy is currently considered an essential component in managing breast cancer patients, particularly those diagnosed at a young age. However, no studies have been published on the feasibility of immediate breast reconstruction in patients diagnosed and operated during the course of gestation. Method: We retrospectively identified all breast cancer patients who were subjected to mastectomy and immediate breast reconstruction during pregnancy at the European Institute of Oncology between 2002 and 2012. Patient demographics, gestational age at surgery, tumor stage, adjuvant treatment, details of the surgical procedures, surgical outcomes and fetal outcomes were analyzed. Results: A total of 78 patients with breast cancer diagnosed during pregnancy were subjected to a surgical procedure during the course of gestation. Twenty-two patients had mastectomy; of whom 13 were subjected to immediate breast reconstruction. Twelve out of 13 patients had a two-stage procedure with tissue expander insertion. Median gestational age at surgery was 16 weeks. No major surgical complications were encountered. Only one patient elected to have an abortion, otherwise, no spontaneous abortions or pregnancy complications were reported. Median gestational age at delivery was 35 weeks (range: 32-40 weeks). No major congenital malformations were reported. At a median follow-up of 32months, all patients are alive with no long-term surgical complications. Conclusions: This is the first study of immediate breast reconstruction in pregnant breast cancer patients. Tissue expander insertion appears to ensure a short operative time, and does not seem to be associated with considerable morbidity to the patient or the fetus. Hence, it could be considered in the multidisciplinary management of women diagnosed with breast cancer during pregnancy.",
keywords = "Breast cancer, Immediate reconstruction, Mastectomy, Pregnancy",
author = "Visnu Lohsiriwat and Peccatori, {Fedro Alessandro} and Stefano Martella and Azim, {Hatem A.} and Sarno, {Maria Anna} and Viviana Galimberti and {De Lorenzi}, Francesca and Mattia Intra and Claudia Sangalli and Nicole Rotmensz and Giancarlo Pruneri and Giuseppe Renne and Schorr, {Mario Casales} and {Nevola Teixeira}, {Luiz Felipe} and Mario Rietjens and Massimo Giroda and Oreste Gentilini",
year = "2013",
month = "10",
doi = "10.1016/j.breast.2013.06.005",
language = "English",
volume = "22",
pages = "657--660",
journal = "Breast",
issn = "0960-9776",
publisher = "Churchill Livingstone",
number = "5",

}

TY - JOUR

T1 - Immediate breast reconstruction with expander in pregnant breast cancer patients

AU - Lohsiriwat, Visnu

AU - Peccatori, Fedro Alessandro

AU - Martella, Stefano

AU - Azim, Hatem A.

AU - Sarno, Maria Anna

AU - Galimberti, Viviana

AU - De Lorenzi, Francesca

AU - Intra, Mattia

AU - Sangalli, Claudia

AU - Rotmensz, Nicole

AU - Pruneri, Giancarlo

AU - Renne, Giuseppe

AU - Schorr, Mario Casales

AU - Nevola Teixeira, Luiz Felipe

AU - Rietjens, Mario

AU - Giroda, Massimo

AU - Gentilini, Oreste

PY - 2013/10

Y1 - 2013/10

N2 - Background: Breast reconstruction after mastectomy is currently considered an essential component in managing breast cancer patients, particularly those diagnosed at a young age. However, no studies have been published on the feasibility of immediate breast reconstruction in patients diagnosed and operated during the course of gestation. Method: We retrospectively identified all breast cancer patients who were subjected to mastectomy and immediate breast reconstruction during pregnancy at the European Institute of Oncology between 2002 and 2012. Patient demographics, gestational age at surgery, tumor stage, adjuvant treatment, details of the surgical procedures, surgical outcomes and fetal outcomes were analyzed. Results: A total of 78 patients with breast cancer diagnosed during pregnancy were subjected to a surgical procedure during the course of gestation. Twenty-two patients had mastectomy; of whom 13 were subjected to immediate breast reconstruction. Twelve out of 13 patients had a two-stage procedure with tissue expander insertion. Median gestational age at surgery was 16 weeks. No major surgical complications were encountered. Only one patient elected to have an abortion, otherwise, no spontaneous abortions or pregnancy complications were reported. Median gestational age at delivery was 35 weeks (range: 32-40 weeks). No major congenital malformations were reported. At a median follow-up of 32months, all patients are alive with no long-term surgical complications. Conclusions: This is the first study of immediate breast reconstruction in pregnant breast cancer patients. Tissue expander insertion appears to ensure a short operative time, and does not seem to be associated with considerable morbidity to the patient or the fetus. Hence, it could be considered in the multidisciplinary management of women diagnosed with breast cancer during pregnancy.

AB - Background: Breast reconstruction after mastectomy is currently considered an essential component in managing breast cancer patients, particularly those diagnosed at a young age. However, no studies have been published on the feasibility of immediate breast reconstruction in patients diagnosed and operated during the course of gestation. Method: We retrospectively identified all breast cancer patients who were subjected to mastectomy and immediate breast reconstruction during pregnancy at the European Institute of Oncology between 2002 and 2012. Patient demographics, gestational age at surgery, tumor stage, adjuvant treatment, details of the surgical procedures, surgical outcomes and fetal outcomes were analyzed. Results: A total of 78 patients with breast cancer diagnosed during pregnancy were subjected to a surgical procedure during the course of gestation. Twenty-two patients had mastectomy; of whom 13 were subjected to immediate breast reconstruction. Twelve out of 13 patients had a two-stage procedure with tissue expander insertion. Median gestational age at surgery was 16 weeks. No major surgical complications were encountered. Only one patient elected to have an abortion, otherwise, no spontaneous abortions or pregnancy complications were reported. Median gestational age at delivery was 35 weeks (range: 32-40 weeks). No major congenital malformations were reported. At a median follow-up of 32months, all patients are alive with no long-term surgical complications. Conclusions: This is the first study of immediate breast reconstruction in pregnant breast cancer patients. Tissue expander insertion appears to ensure a short operative time, and does not seem to be associated with considerable morbidity to the patient or the fetus. Hence, it could be considered in the multidisciplinary management of women diagnosed with breast cancer during pregnancy.

KW - Breast cancer

KW - Immediate reconstruction

KW - Mastectomy

KW - Pregnancy

UR - http://www.scopus.com/inward/record.url?scp=84884142710&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84884142710&partnerID=8YFLogxK

U2 - 10.1016/j.breast.2013.06.005

DO - 10.1016/j.breast.2013.06.005

M3 - Article

C2 - 23871328

AN - SCOPUS:84884142710

VL - 22

SP - 657

EP - 660

JO - Breast

JF - Breast

SN - 0960-9776

IS - 5

ER -