Immediate hypersensitivity gastropathy and duodenogastric reflux

L. Celli, P. Granelli, B. Brando, L. Bertuglia

Research output: Contribution to journalArticlepeer-review


The purpose of the present study was to define a correlation between immediate hypersensitivity gastropathy and duodenogastric reflux. The gastric mucosa can often be involved in immediate hypersensitivity reactions, mainly in atopic subjects suffering from other allergic diseases. The typical endoscopic findings concern alterations of the gastric mucosa, like pomphi and variolae, and alterations of the gastric motility, like spasms and pyloric disturbances, all of them occurring in the antrum in most cases. Histology and immunofluorescence show peculiar patterns. Bile reflux is present in over 50% of these patients. The possible relationship between duodenogastric reflux and the gastric hypersensitivity reactions is briefly discussed in the light of what is known about the action of bile on the gastric barrier.

Original languageEnglish
Pages (from-to)129-130
Number of pages2
JournalScandinavian Journal of Gastroenterology, Supplement
Issue number67
Publication statusPublished - 1981

ASJC Scopus subject areas

  • Gastroenterology


Dive into the research topics of 'Immediate hypersensitivity gastropathy and duodenogastric reflux'. Together they form a unique fingerprint.

Cite this