Immune complexes (IC) have been detected in 9 out of 15 patients presenting with idiopathic aplastic anemia using the polymorphonuclear neutrophil immunohistochemical technique. Immunosuppressive treatment undertaken in one patient produced a gradual recovery, the bone marrow repopulation being paralleled by the disappearance of IC. The significance of IC in aplastic anemia and the relationship with possible pathogenesis and therapy of the disease are discussed.
|Number of pages||7|
|Journal||British Journal of Haematology|
|Publication status||Published - 1980|
ASJC Scopus subject areas