Immune mechanisms in neoplasia

Chiara Castelli, Piero Dalerba, Chiara Casati, Luisa Novellino, Giorgio Parmiani, Annamaria De Filippo

Research output: Contribution to journalArticlepeer-review


Tumor can be recognized by the immune system the witnessed extraordinary advances in our understanding of tumor-host interactions. Here, we review evidence supporting the double role of the adaptive immune system in exerting both host-protecting tumor-shaping actions. We will then some of the molecular mechanisms of the adaptive immune response tumor to grow in an immonocompetent host, along with strategies that can potentially overcome the ability of the tumor to evade the immune system.

Original languageEnglish
Pages (from-to)375-381
Number of pages7
JournalDrug Discovery Today: Disease Mechanisms
Issue number3
Publication statusPublished - Dec 2004

ASJC Scopus subject areas

  • Molecular Medicine
  • Drug Discovery


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