Abstract
Cases of acquired rippling muscle disease in association with myasthenia gravis have been reported. We present three patients with iRMD (immune-mediated rippling muscle disease) and AChR-antibody positive myasthenia gravis. None of them had thymus pathology. They presented exercise-induced muscle rippling combined with generalized myasthenia gravis. One of them had muscle biopsy showing a myopathic pattern and a patchy immunostaining with caveolin antibodies. They were successfully treated steroids and azathioprine. The immune nature of this association is supported by the response to immunotherapies and the positivity of AChR-antibodies.
Original language | English |
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Pages (from-to) | 59-61 |
Number of pages | 3 |
Journal | Journal of Neuroimmunology |
Volume | 299 |
DOIs | |
Publication status | Published - Oct 15 2016 |
Keywords
- AchR antibodies
- Autoimmune
- Caveolin
- Myasthenia
- Rippling
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Medicine(all)
- Neurology
- Clinical Neurology