Immune reconstitution inflammatory syndrome associated with Aspergillus terreus pulmonary infection in an autologous stem cell transplant recipient: Case report

S. Antinori, M. Corbellino, A. Necchi, P. Corradini, C. Vismara, V. Montefusco, A. M. Gianni

Research output: Contribution to journalArticlepeer-review

Abstract

We describe an autologous stem cell transplant recipient who developed immune reconstitution inflammatory syndrome (IRIS) associated with Aspergillus terreus invasive pulmonary infection after recovery from neutropenia. Clinical and radiological worsening of pulmonary invasive aspergillosis coincident with a robust decline of serum galactomannan values and rising neutrophil counts should be interpreted as IRIS and should not require changes to antifungal therapy.

Original languageEnglish
Pages (from-to)64-68
Number of pages5
JournalTransplant Infectious Disease
Volume12
Issue number1
DOIs
Publication statusPublished - Feb 2010

Keywords

  • Aspergillus terreus
  • Galactomannan
  • Immune reconstitution inflammatory syndrome
  • Stem cell transplant

ASJC Scopus subject areas

  • Transplantation
  • Infectious Diseases

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