Abstract
We recently reported that variable expression of immune-response genes distinguishes tumor positive sentinel nodes in melanoma patients with malignant progression from those with non-progressing disease. Our results depict sentinel nodes as sites in which immune functions are associated with metastatic disease and identify CD30 as a host immune-related cancer prognostic marker and potential therapeutic target.
| Original language | English |
|---|---|
| Article number | e28498 |
| Journal | OncoImmunology |
| Volume | 3 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2014 |
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Keywords
- CD30
- Expression profiles
- Lymph node
- Melanoma
- Sentinel node
ASJC Scopus subject areas
- Immunology and Allergy
- Oncology
- Immunology
Cite this
Immune response markers in sentinel nodes may predict melanoma progression. / Rodolfo, Monica; Castelli, Chiara; Rivoltini, Licia.
In: OncoImmunology, Vol. 3, No. 4, e28498, 2014.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Immune response markers in sentinel nodes may predict melanoma progression
AU - Rodolfo, Monica
AU - Castelli, Chiara
AU - Rivoltini, Licia
PY - 2014
Y1 - 2014
N2 - We recently reported that variable expression of immune-response genes distinguishes tumor positive sentinel nodes in melanoma patients with malignant progression from those with non-progressing disease. Our results depict sentinel nodes as sites in which immune functions are associated with metastatic disease and identify CD30 as a host immune-related cancer prognostic marker and potential therapeutic target.
AB - We recently reported that variable expression of immune-response genes distinguishes tumor positive sentinel nodes in melanoma patients with malignant progression from those with non-progressing disease. Our results depict sentinel nodes as sites in which immune functions are associated with metastatic disease and identify CD30 as a host immune-related cancer prognostic marker and potential therapeutic target.
KW - CD30
KW - Expression profiles
KW - Lymph node
KW - Melanoma
KW - Sentinel node
UR - http://www.scopus.com/inward/record.url?scp=84902603313&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84902603313&partnerID=8YFLogxK
U2 - 10.4161/onci.28498
DO - 10.4161/onci.28498
M3 - Article
AN - SCOPUS:84902603313
VL - 3
JO - OncoImmunology
JF - OncoImmunology
SN - 2162-4011
IS - 4
M1 - e28498
ER -