Immune responses to tumour and embryo cells in patients with mammary carcinoma

G. Della Porta, S. Canevari, G. Fossati

Research output: Contribution to journalArticlepeer-review

Abstract

Cytotoxicity microassays were used to study cellular and humoral responses of patients with breast carcinoma against in vitro cultured target cells of breast carcinomata and of human embryos. Peripheral lymphocytes were cytotoxic on both target cell types, whereas sera exerted a complement dependent cytotoxicity on breast cancer cells only. The immunosensitivity of the breast cancer cells to patient lymphocytes was augmented by restraining cell growth before test with a decreased quantity of foetal calf serum.

Original languageEnglish
Pages (from-to)103-107
Number of pages5
JournalBritish Journal of Cancer
Volume28
Issue numberSup. 1
Publication statusPublished - 1973

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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