Abstract
Cytotoxicity microassays were used to study cellular and humoral responses of patients with breast carcinoma against in vitro cultured target cells of breast carcinomata and of human embryos. Peripheral lymphocytes were cytotoxic on both target cell types, whereas sera exerted a complement dependent cytotoxicity on breast cancer cells only. The immunosensitivity of the breast cancer cells to patient lymphocytes was augmented by restraining cell growth before test with a decreased quantity of foetal calf serum.
| Original language | English |
|---|---|
| Pages (from-to) | 103-107 |
| Number of pages | 5 |
| Journal | British Journal of Cancer |
| Volume | 28 |
| Issue number | Sup. 1 |
| Publication status | Published - 1973 |
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ASJC Scopus subject areas
- Cancer Research
- Oncology
Cite this
Immune responses to tumour and embryo cells in patients with mammary carcinoma. / Della Porta, G.; Canevari, S.; Fossati, G.
In: British Journal of Cancer, Vol. 28, No. Sup. 1, 1973, p. 103-107.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Immune responses to tumour and embryo cells in patients with mammary carcinoma
AU - Della Porta, G.
AU - Canevari, S.
AU - Fossati, G.
PY - 1973
Y1 - 1973
N2 - Cytotoxicity microassays were used to study cellular and humoral responses of patients with breast carcinoma against in vitro cultured target cells of breast carcinomata and of human embryos. Peripheral lymphocytes were cytotoxic on both target cell types, whereas sera exerted a complement dependent cytotoxicity on breast cancer cells only. The immunosensitivity of the breast cancer cells to patient lymphocytes was augmented by restraining cell growth before test with a decreased quantity of foetal calf serum.
AB - Cytotoxicity microassays were used to study cellular and humoral responses of patients with breast carcinoma against in vitro cultured target cells of breast carcinomata and of human embryos. Peripheral lymphocytes were cytotoxic on both target cell types, whereas sera exerted a complement dependent cytotoxicity on breast cancer cells only. The immunosensitivity of the breast cancer cells to patient lymphocytes was augmented by restraining cell growth before test with a decreased quantity of foetal calf serum.
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UR - http://www.scopus.com/inward/citedby.url?scp=0015896762&partnerID=8YFLogxK
M3 - Article
C2 - 4804274
AN - SCOPUS:0015896762
VL - 28
SP - 103
EP - 107
JO - British Journal of Cancer
JF - British Journal of Cancer
SN - 0007-0920
IS - Sup. 1
ER -