Immunity, inflammation and infections during aging: The susceptibility to infections in elderly individuals

Miriam Capri, Stefano Salvioli, Federica Sevini, Elisa Cevenini, Michela Pierini, Laura Celani, Laura Bucci, Rita Ostan, Maria Scurti, Daniela Mazza, Daniela Monti, Claudio Franceschi

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The major changes occurring life long in the human immune system are here described. The progressive inflammatory status which is established during aging together with the progressive susceptibility to infectious diseases are discussed in the frame of the genetic variant influence. Finally, the possibility to counteract the susceptibility to infections by coping with or slowing down immunosenescence, using different molecules or strategies, is argued

Original languageEnglish
Title of host publicationPrevention and Treatment of Age-related Diseases
PublisherSpringer Netherlands
Pages15-29
Number of pages15
ISBN (Print)140204884X, 9781402048845
DOIs
Publication statusPublished - 2006

Keywords

  • Aging
  • Anti-immunosenescence
  • Cytokines
  • Genes
  • Immunity
  • Infectious
  • Inflammation
  • Macrophage
  • T lymphocyte

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Capri, M., Salvioli, S., Sevini, F., Cevenini, E., Pierini, M., Celani, L., Bucci, L., Ostan, R., Scurti, M., Mazza, D., Monti, D., & Franceschi, C. (2006). Immunity, inflammation and infections during aging: The susceptibility to infections in elderly individuals. In Prevention and Treatment of Age-related Diseases (pp. 15-29). Springer Netherlands. https://doi.org/10.1007/1-4020-5058-5_2