Immunization coverage and timeliness of vaccination in Italian children with chronic diseases

E. Pandolfi, E. Carloni, M. G. Marino, M. L. Ciofi degli Atti, F. Gesualdo, M. Romano, A. Giannattasio, A. Guarino, R. Carloni, P. Borgia, E. Volpe, F. Perrelli, R. Pizzuti, A. E. Tozzi

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Since children with chronic diseases represent a primary target for immunization strategies, it is important that their immunization coverage and timeliness of vaccines is optimal. We performed a study to measure immunization coverage and timeliness of vaccines in children with type 1 diabetes, HIV infection, Down syndrome, cystic fibrosis, and neurological diseases. A total of 275 children aged 6 months-18 years were included in the study. Coverage for diphtheria-tetanus-pertussis (DTP), polio (Pol), and hepatitis B (HBV) vaccines approximated 85% at 24 months, while measles-mumps-rubella (MMR) coverage was 62%. Immunization coverage for seasonal influenza was 59%. The analysis of timeliness revealed that there was heterogeneity among children with different chronic diseases. A proportional hazard model showed that children with HIV infection had the longest time to complete three doses of DTP, Pol, and HBV, and those with neurological diseases received the first dose of MMR later than the other categories. Causes of missing or delayed vaccination mostly included a concurrent acute disease. Children with chronic diseases should be strictly monitored for routine and recommended vaccinations, and health care providers and families should be properly informed to avoid false contraindications.

Original languageEnglish
Pages (from-to)5172-5178
Number of pages7
JournalVaccine
Volume30
Issue number34
DOIs
Publication statusPublished - Jul 20 2012

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chronic diseases
Immunization
immunization
Vaccination
Chronic Disease
vaccination
whooping cough
Mumps
Diphtheria
Rubella
Whooping Cough
tetanus
Tetanus
Measles
HIV infections
Poliomyelitis
vaccines
HIV Infections
Vaccines
Down syndrome

Keywords

  • Chronic diseases
  • Immunization coverage
  • Italy
  • Timeliness

ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Infectious Diseases
  • Public Health, Environmental and Occupational Health
  • veterinary(all)
  • Molecular Medicine

Cite this

Immunization coverage and timeliness of vaccination in Italian children with chronic diseases. / Pandolfi, E.; Carloni, E.; Marino, M. G.; Ciofi degli Atti, M. L.; Gesualdo, F.; Romano, M.; Giannattasio, A.; Guarino, A.; Carloni, R.; Borgia, P.; Volpe, E.; Perrelli, F.; Pizzuti, R.; Tozzi, A. E.

In: Vaccine, Vol. 30, No. 34, 20.07.2012, p. 5172-5178.

Research output: Contribution to journalArticle

Pandolfi, E, Carloni, E, Marino, MG, Ciofi degli Atti, ML, Gesualdo, F, Romano, M, Giannattasio, A, Guarino, A, Carloni, R, Borgia, P, Volpe, E, Perrelli, F, Pizzuti, R & Tozzi, AE 2012, 'Immunization coverage and timeliness of vaccination in Italian children with chronic diseases', Vaccine, vol. 30, no. 34, pp. 5172-5178. https://doi.org/10.1016/j.vaccine.2011.02.099
Pandolfi, E. ; Carloni, E. ; Marino, M. G. ; Ciofi degli Atti, M. L. ; Gesualdo, F. ; Romano, M. ; Giannattasio, A. ; Guarino, A. ; Carloni, R. ; Borgia, P. ; Volpe, E. ; Perrelli, F. ; Pizzuti, R. ; Tozzi, A. E. / Immunization coverage and timeliness of vaccination in Italian children with chronic diseases. In: Vaccine. 2012 ; Vol. 30, No. 34. pp. 5172-5178.
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