Immunocytochemical evidence for glutamatergic cortico-cortical connections in monkeys

Fiorenzo Conti, Mara Fabri, Tullio Manzoni

Research output: Contribution to journalArticlepeer-review

Abstract

Retrograde transport of horseradish peroxidase and immunocytochemical visualization of glutamate (Glu) were combined to investigate the neurotransmitter used by cortico-cortical neurons in the first (SI) and second (SII) somatic sensory areas of macaque monkeys. The majority of association and callosal neurons in SI and SII were immunoreactive for an antiGlu serum; evidence was therefore obtained in support of a role for Glu, or a closely related compound, as the synaptic transmitter used by cortico-cortical fibers.

Original languageEnglish
Pages (from-to)148-153
Number of pages6
JournalBrain Research
Volume462
Issue number1
DOIs
Publication statusPublished - Oct 11 1988

Keywords

  • Cortico-cortical connection
  • Glutamate
  • Immunocytochemistry
  • Monkey
  • Somatic sensory cortex

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

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