TY - JOUR
T1 - Immunoelectron microscopy of different forms of glomerulonephritis in routine biopsy material
AU - Ihling, Ch
AU - Olivieri, V.
AU - Banfi, G.
AU - Fogazzi, B.
AU - Edefonti, A.
AU - Gudat, F.
AU - Mihatsch, M. J.
PY - 1994
Y1 - 1994
N2 - Renal biospies were investigated of patients with IgA or membraneous glomerulonephritis or with systemic lupus erythematosus by light microscopy, electron microscopy, light microscopic immunohistology and by immunoelectron microscopy using the postembedding technique applied to LR-White embedded tissue. Aim of the study was to explore whether immunoelectron microscopy is reproduced on routine biopsy material and in accordance with light microscopic immunohistological findings. The study shows that immunoelectron microscopy can be applied to routine biopsy material and gives reproducible results. The applied method proved to be reliable, and, hence, routine biopsy material may be used for further studies concerning subcellular mechanisms in immunocomplex deposition and removal.
AB - Renal biospies were investigated of patients with IgA or membraneous glomerulonephritis or with systemic lupus erythematosus by light microscopy, electron microscopy, light microscopic immunohistology and by immunoelectron microscopy using the postembedding technique applied to LR-White embedded tissue. Aim of the study was to explore whether immunoelectron microscopy is reproduced on routine biopsy material and in accordance with light microscopic immunohistological findings. The study shows that immunoelectron microscopy can be applied to routine biopsy material and gives reproducible results. The applied method proved to be reliable, and, hence, routine biopsy material may be used for further studies concerning subcellular mechanisms in immunocomplex deposition and removal.
KW - Immunoelectron microscopy
KW - Kidney
KW - Routine biopsy material
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M3 - Article
C2 - 7991462
AN - SCOPUS:0028225580
VL - 190
SP - 417
EP - 422
JO - Pathology Research and Practice
JF - Pathology Research and Practice
SN - 0344-0338
IS - 5
ER -