Immunohistochemical detection of folliculo-stellate cells in human pituitary adenomas

Libero Lauriola, Domenico Cocchia, Steno Sentinelli, Nicola Maggiano, Giulio Maira, Fabrizio Michetti

Research output: Contribution to journalArticlepeer-review


In the light of recent findings concerning the presence of S-100 antigen in folliculo-stellate cells of the rat adenohypophysis, we investigated the possible presence of S-100-labelled cells in both the normal human adenohypophysis and in pituitary adenomas. Immunostaining enabled us to detect, with both light and electron microscopy, the presence of S-100-labelled folliculo-stellate cells in a significant number of pituitary adenomas, mostly growth-hormone secreting, and, as expected, in the normal human adenohypophysis.

Original languageEnglish
Pages (from-to)189-197
Number of pages9
JournalVirchows Archiv B Cell Pathology Including Molecular Pathology
Issue number1
Publication statusPublished - Dec 1984


  • Folliculo-stellate cells
  • immunohistochemistry
  • Pituitary adenomas
  • S-100 antigen

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medicine(all)


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