Immunohistochemistry of bone-marrow biopsy

Stefano A. Pileri, Giovanna Roncador, Claudio Ceccarelli, Milena Piccioli, Elena Sabattini, Aspasia Briskomatis, Donatella Santini, Ornella Leone, Pier Paolo Piccaluga, Lorenzo Leoncini, Brunangelo Falini

Research output: Contribution to journalArticlepeer-review

Abstract

In a percentage of cases, conventional morphologic evaluation of bone-marrow needle biopsy (BMNB) in insufficient to achieve a firm diagnosis. Under these circumstances, immunohistochemistry plays a basic role, providing an easy and objective key for the interpretation of the pattern observed in most instances. Herein, the authors focus on the technical procedures, which allow extensive application of immunohistochemistry to the study of BMNB, as well as on the panels of antibodies needed for the identification of the most relevant conditions.

Original languageEnglish
Pages (from-to)69-75
Number of pages7
JournalLeukemia and Lymphoma
Volume26
Issue numberSUPPL. 1
Publication statusPublished - 1997

Keywords

  • Bone-marrow biopsy
  • Immunohistochemistry
  • Leukaemia
  • Lymphoma

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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