Advances in understanding of bronchial asthma are to be expected from more detailed information on the immuno-pathological mechanisms involved. Reaginic IgE antibodies are responsible for the great majority of cases of extrinsic asthma, but in some cases immune complexes may also be important. Great progress has been achieved after reproducible methods for detecting cellular and serum specific IgE antibodies were introduced. Moreover, the immunological and biological changes induced by immunotherapy are better known. Standardization and purification of allergenic extracts is now under study in many laboratories, our own included. Concerning intrinsic asthma, attempts to demonstrate the importance of (auto) immune mechanisms have been performed. The results of these studies are reported.
|Translated title of the contribution||Immunologic aspects of bronchial asthma|
|Number of pages||12|
|Publication status||Published - 1978|
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine