Immunological and virological aspects of autologous stem cell transplantation in HIV+ patients

Paolo De Paoli

Research output: Contribution to journalArticlepeer-review

Abstract

Autologous stem cell transplantation (ASCT) is an effective therapeutic option in patients with human immunodeficiency virus-associated lymphomas (HIV-L). This review will focus on the experimental and clinical data regarding the effects of ASCT on the reconstitution of lymphocyte subsets, T-cell repertoire and thymic function in HIV-L patients. Current data on the kinetics of reactivation of HIV, Epstein-Barr virus, cytomegalovirus and hepatitis C virus during mobilization and after reinfusion of stem cells will be also analyzed.

Original languageEnglish
Pages (from-to)2563-2568
Number of pages6
JournalMicrobes and Infection
Volume8
Issue number9-10
DOIs
Publication statusPublished - Aug 2006

Keywords

  • Autologous stem cell transplantation
  • HIV
  • Immunology
  • Virology

ASJC Scopus subject areas

  • Microbiology
  • Infectious Diseases

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