Immunological characterization of renal glycosuria patients

P. de Paoli, S. Battistin, A. Jus, M. Reitano, D. Villalta, S. De Marchi, E. Cecchin, A. Basile, G. Santini

Research output: Contribution to journalArticlepeer-review

Abstract

We have evaluated the autoantibody pattern, the production of specific immunoglobulins against bacteria in the urinary tract and lymphocytes populations in peripheral blood of primary renal glycosuria patients. All the affected members present autoantibodies against various antigens. In nine patients immunofluorescence revealed antibody coated bacteria in urine specimens. Imbalances in lymphocytes subpopulations are also present, with a reduction of OKT8+ cells and an increase of B and natural killer cells. These results support previous observations about immunological abnormalities in these patients.

Original languageEnglish
Pages (from-to)289-294
Number of pages6
JournalClinical and Experimental Immunology
Volume56
Issue number2
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Immunology

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