We analyzed a cohort of intravenous drug abusers with HIV-1 disease attending our institute in the years 1985-1993. We focused particular attention on the epidemiological analysis of patients, and their clinical, immunological and infectious conditions. The significance of biological markers, particulary CD4+ lymphocyte count and the occurence of other viral infections such as Cytomegalovirus, Epstein-Barr virus, Herpes Simplex virus and Hepatitis B and C viruses in the progress of HIV-1 disease were evaluated. At least two-thirds of the patients at different stages of HIV-1 were treated with antiretroviral drugs: zidovudine (AZT) from 1987 up to the present and more recently didanosine (DDI) alone or in combination with AZT. Psychological and behavioral aspects of our HIV-1 infected drug abusers, in particular needle exchange and condom use, were analyzed.
|Number of pages||16|
|Journal||Journal of Drug Issues|
|Publication status||Published - 1994|
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Pathology and Forensic Medicine
- Health(social science)