TY - JOUR
T1 - Immunological, clinical and epidemiological aspects of an HIV-1 positive drug abuser cohort
AU - Mezzaroma, I.
AU - D'Offizi, G.
AU - Pinter, E.
AU - Ferrara, R.
AU - Rosso, R.
AU - Guerra, E.
AU - Ricci, G.
AU - Carta, M.
AU - Angelini, S.
AU - Aiuti, F.
PY - 1994
Y1 - 1994
N2 - We analyzed a cohort of intravenous drug abusers with HIV-1 disease attending our institute in the years 1985-1993. We focused particular attention on the epidemiological analysis of patients, and their clinical, immunological and infectious conditions. The significance of biological markers, particulary CD4+ lymphocyte count and the occurence of other viral infections such as Cytomegalovirus, Epstein-Barr virus, Herpes Simplex virus and Hepatitis B and C viruses in the progress of HIV-1 disease were evaluated. At least two-thirds of the patients at different stages of HIV-1 were treated with antiretroviral drugs: zidovudine (AZT) from 1987 up to the present and more recently didanosine (DDI) alone or in combination with AZT. Psychological and behavioral aspects of our HIV-1 infected drug abusers, in particular needle exchange and condom use, were analyzed.
AB - We analyzed a cohort of intravenous drug abusers with HIV-1 disease attending our institute in the years 1985-1993. We focused particular attention on the epidemiological analysis of patients, and their clinical, immunological and infectious conditions. The significance of biological markers, particulary CD4+ lymphocyte count and the occurence of other viral infections such as Cytomegalovirus, Epstein-Barr virus, Herpes Simplex virus and Hepatitis B and C viruses in the progress of HIV-1 disease were evaluated. At least two-thirds of the patients at different stages of HIV-1 were treated with antiretroviral drugs: zidovudine (AZT) from 1987 up to the present and more recently didanosine (DDI) alone or in combination with AZT. Psychological and behavioral aspects of our HIV-1 infected drug abusers, in particular needle exchange and condom use, were analyzed.
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M3 - Article
AN - SCOPUS:0027948548
VL - 24
SP - 657
EP - 672
JO - Journal of Drug Issues
JF - Journal of Drug Issues
SN - 0022-0426
IS - 4
ER -