Immunological comorbity in coeliac disease: Associations, risk factors and clinical implications

Luca Elli, Antonella Bonura, Daniela Garavaglia, Eliana Rulli, Irene Floriani, Giovanna Tagliabue, Paolo Contiero, Maria Teresa Bardella

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Purpose: Coeliac disease is frequently associated with other immunomediated diseases. Our aim was to identify immunological comorbidities and possible risk factors for their development in coeliac patients. Methods: We recruited a cohort of 1,015 coeliac patients followed from 0 to 46 years in a single tertiary referral centre. Data were collected from the yearly scheduled clinical and serological evaluations. Possible risk factors such as demographic parameters, type of symptomatic presentation, gluten exposure, gluten-free diet compliance and family history were all evaluated. Subjects (848,606) from the regional health registry were investigated as controls. Results: The prevalence of immunomediated diseases was higher in patients with coeliac disease compared to the registry population (23 % vs 0.4 %, p

Original languageEnglish
Pages (from-to)984-990
Number of pages7
JournalJournal of Clinical Immunology
Volume32
Issue number5
DOIs
Publication statusPublished - Oct 2012

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Celiac Disease
Abdomen
Registries
Gluten-Free Diet
Glutens
Tertiary Care Centers
Comorbidity
Demography
Health
Population

Keywords

  • Antibodies
  • Coeliac disease
  • Gluten free diet
  • Immunomediated disorder

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Immunological comorbity in coeliac disease : Associations, risk factors and clinical implications. / Elli, Luca; Bonura, Antonella; Garavaglia, Daniela; Rulli, Eliana; Floriani, Irene; Tagliabue, Giovanna; Contiero, Paolo; Bardella, Maria Teresa.

In: Journal of Clinical Immunology, Vol. 32, No. 5, 10.2012, p. 984-990.

Research output: Contribution to journalArticle

Elli, Luca ; Bonura, Antonella ; Garavaglia, Daniela ; Rulli, Eliana ; Floriani, Irene ; Tagliabue, Giovanna ; Contiero, Paolo ; Bardella, Maria Teresa. / Immunological comorbity in coeliac disease : Associations, risk factors and clinical implications. In: Journal of Clinical Immunology. 2012 ; Vol. 32, No. 5. pp. 984-990.
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