Immunological features of diffuse connective tissue diseases

G. R. Burgio, A. Martini

Research output: Contribution to journalArticlepeer-review


Diffuse connective tissue diseases (DCTD) represent an heterogeneous group of disorders characterized by systemic inflammatory reactions that are currently classified on clinical grounds. Their aetiopathogenesis is largely unknown and appears to be very complex, associating exogenous factors with an immunogenetic predisposition. In the last decade, studies on human leukocyte antigen (HLA)-disease associations and antinuclear antibodies have provided some useful clues for the diagnosis and clinical management of DCTD.

Original languageEnglish
Pages (from-to)224-231
Number of pages8
JournalEuropean Journal of Pediatrics
Issue number4
Publication statusPublished - Jan 1990


  • Antinuclear antibodies
  • Diffuse connective tissue diseases
  • Human leukocyte antigens (HLA)

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Fingerprint Dive into the research topics of 'Immunological features of diffuse connective tissue diseases'. Together they form a unique fingerprint.

Cite this