Immunological imbalance in uncomplicated chronic alcoholism

Giambattista Bonanno; Giulia Bocchini; Aldo Canevari; Francesco Pieri; Silvano Ferrini; Giovanni Melioli

doi:10.1016/0376-8716(83)90044-3

Immunological imbalance in uncomplicated chronic alcoholism

Giambattista Bonanno, Giulia Bocchini, Aldo Canevari, Francesco Pieri, Silvano Ferrini, Giovanni Melioli

A.O.U. San Martino - IST, Istituto Nazionale Ricerca sul Cancro (GENOVA)

Research output: Contribution to journal › Article › peer-review

Abstract

The lymphocyte response to unspecific mitogenic lectins and the frequency of the lymphocytary populations and two subpopulations (DR-and Fcγ-positive T-cells) as well as the serum immunoglobulin levels were tested. Blood samples were drawn from 15 volunteers with chronic alcoholism, and no clinical detectable correlated diseases and from 8 healthy subjects as controls. An activation of the immune system was found, characterized by an increase of T lymphocytes, DR-positive T-cells, IgA and IgG. Aspects of this activation are discussed.

Original language	English
Pages (from-to)	189-196
Number of pages	8
Journal	Drug and Alcohol Dependence
Volume	12
Issue number	2
DOIs	https://doi.org/10.1016/0376-8716(83)90044-3
Publication status	Published - 1983

Keywords

Alcoholism
Immunity
Lymphocytes

ASJC Scopus subject areas

Medicine(all)
Behavioral Neuroscience
Toxicology
Health(social science)

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10.1016/0376-8716(83)90044-3

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AU - Bonanno, Giambattista

AU - Bocchini, Giulia

AU - Canevari, Aldo

AU - Pieri, Francesco

AU - Ferrini, Silvano

AU - Melioli, Giovanni

PY - 1983

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AB - The lymphocyte response to unspecific mitogenic lectins and the frequency of the lymphocytary populations and two subpopulations (DR-and Fcγ-positive T-cells) as well as the serum immunoglobulin levels were tested. Blood samples were drawn from 15 volunteers with chronic alcoholism, and no clinical detectable correlated diseases and from 8 healthy subjects as controls. An activation of the immune system was found, characterized by an increase of T lymphocytes, DR-positive T-cells, IgA and IgG. Aspects of this activation are discussed.

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KW - Immunity

KW - Lymphocytes

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