Immunological imbalance in uncomplicated chronic alcoholism

Giambattista Bonanno, Giulia Bocchini, Aldo Canevari, Francesco Pieri, Silvano Ferrini, Giovanni Melioli

Research output: Contribution to journalArticle

Abstract

The lymphocyte response to unspecific mitogenic lectins and the frequency of the lymphocytary populations and two subpopulations (DR-and Fcγ-positive T-cells) as well as the serum immunoglobulin levels were tested. Blood samples were drawn from 15 volunteers with chronic alcoholism, and no clinical detectable correlated diseases and from 8 healthy subjects as controls. An activation of the immune system was found, characterized by an increase of T lymphocytes, DR-positive T-cells, IgA and IgG. Aspects of this activation are discussed.

Original languageEnglish
Pages (from-to)189-196
Number of pages8
JournalDrug and Alcohol Dependence
Volume12
Issue number2
DOIs
Publication statusPublished - 1983

Fingerprint

T-cells
alcoholism
activation
Alcoholism
T-Lymphocytes
Chemical activation
Lymphocytes
Immune system
Disease
Lectins
Immunoglobulin A
Immunoglobulins
Volunteers
Immune System
Healthy Volunteers
Blood
Immunoglobulin G
Serum
Population

Keywords

  • Alcoholism
  • Immunity
  • Lymphocytes

ASJC Scopus subject areas

  • Medicine(all)
  • Behavioral Neuroscience
  • Toxicology
  • Health(social science)

Cite this

Bonanno, G., Bocchini, G., Canevari, A., Pieri, F., Ferrini, S., & Melioli, G. (1983). Immunological imbalance in uncomplicated chronic alcoholism. Drug and Alcohol Dependence, 12(2), 189-196. https://doi.org/10.1016/0376-8716(83)90044-3

Immunological imbalance in uncomplicated chronic alcoholism. / Bonanno, Giambattista; Bocchini, Giulia; Canevari, Aldo; Pieri, Francesco; Ferrini, Silvano; Melioli, Giovanni.

In: Drug and Alcohol Dependence, Vol. 12, No. 2, 1983, p. 189-196.

Research output: Contribution to journalArticle

Bonanno, G, Bocchini, G, Canevari, A, Pieri, F, Ferrini, S & Melioli, G 1983, 'Immunological imbalance in uncomplicated chronic alcoholism', Drug and Alcohol Dependence, vol. 12, no. 2, pp. 189-196. https://doi.org/10.1016/0376-8716(83)90044-3
Bonanno G, Bocchini G, Canevari A, Pieri F, Ferrini S, Melioli G. Immunological imbalance in uncomplicated chronic alcoholism. Drug and Alcohol Dependence. 1983;12(2):189-196. https://doi.org/10.1016/0376-8716(83)90044-3
Bonanno, Giambattista ; Bocchini, Giulia ; Canevari, Aldo ; Pieri, Francesco ; Ferrini, Silvano ; Melioli, Giovanni. / Immunological imbalance in uncomplicated chronic alcoholism. In: Drug and Alcohol Dependence. 1983 ; Vol. 12, No. 2. pp. 189-196.
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