Immunological imbalance in uncomplicated chronic alcoholism

Giambattista Bonanno, Giulia Bocchini, Aldo Canevari, Francesco Pieri, Silvano Ferrini, Giovanni Melioli

Research output: Contribution to journalArticlepeer-review


The lymphocyte response to unspecific mitogenic lectins and the frequency of the lymphocytary populations and two subpopulations (DR-and Fcγ-positive T-cells) as well as the serum immunoglobulin levels were tested. Blood samples were drawn from 15 volunteers with chronic alcoholism, and no clinical detectable correlated diseases and from 8 healthy subjects as controls. An activation of the immune system was found, characterized by an increase of T lymphocytes, DR-positive T-cells, IgA and IgG. Aspects of this activation are discussed.

Original languageEnglish
Pages (from-to)189-196
Number of pages8
JournalDrug and Alcohol Dependence
Issue number2
Publication statusPublished - 1983


  • Alcoholism
  • Immunity
  • Lymphocytes

ASJC Scopus subject areas

  • Medicine(all)
  • Behavioral Neuroscience
  • Toxicology
  • Health(social science)


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