TY - JOUR
T1 - Immunological imbalance in uncomplicated chronic alcoholism
AU - Bonanno, Giambattista
AU - Bocchini, Giulia
AU - Canevari, Aldo
AU - Pieri, Francesco
AU - Ferrini, Silvano
AU - Melioli, Giovanni
PY - 1983
Y1 - 1983
N2 - The lymphocyte response to unspecific mitogenic lectins and the frequency of the lymphocytary populations and two subpopulations (DR-and Fcγ-positive T-cells) as well as the serum immunoglobulin levels were tested. Blood samples were drawn from 15 volunteers with chronic alcoholism, and no clinical detectable correlated diseases and from 8 healthy subjects as controls. An activation of the immune system was found, characterized by an increase of T lymphocytes, DR-positive T-cells, IgA and IgG. Aspects of this activation are discussed.
AB - The lymphocyte response to unspecific mitogenic lectins and the frequency of the lymphocytary populations and two subpopulations (DR-and Fcγ-positive T-cells) as well as the serum immunoglobulin levels were tested. Blood samples were drawn from 15 volunteers with chronic alcoholism, and no clinical detectable correlated diseases and from 8 healthy subjects as controls. An activation of the immune system was found, characterized by an increase of T lymphocytes, DR-positive T-cells, IgA and IgG. Aspects of this activation are discussed.
KW - Alcoholism
KW - Immunity
KW - Lymphocytes
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U2 - 10.1016/0376-8716(83)90044-3
DO - 10.1016/0376-8716(83)90044-3
M3 - Article
C2 - 6606552
AN - SCOPUS:0020972786
VL - 12
SP - 189
EP - 196
JO - Drug and Alcohol Dependence
JF - Drug and Alcohol Dependence
SN - 0376-8716
IS - 2
ER -