Immunopathogenetic and pharmacological aspects of interstitial lung diseases.

G. Mazzoccoli, A. De Cata, G. D. De Pinto, A. De Matthaeis, G. Vendemiale

Research output: Contribution to journalArticlepeer-review

Abstract

Interstitial lung diseases (ILDs) are inflammatory diseases characterized by slow and progressive destruction of alveolar-capillary functional units, often leading to respiratory failure and death. A first stage of alveolitis and a following stage of fibrosis provoke an anatomical distortion of the peripheral airways and the interstitium, and for their smoldering evolution and non-specificity of symptoms ILDs may remain undiagnosed and untreated for a long time. In this review we exploited the immunopathogenetic aspects and the therapeutical approaches to this frequently unrecognized and severe disease.

Original languageEnglish
Pages (from-to)971-980
Number of pages10
JournalInternational Journal of Immunopathology and Pharmacology
Volume23
Issue number4
Publication statusPublished - Oct 2010

ASJC Scopus subject areas

  • Pharmacology
  • Immunology
  • Immunology and Allergy

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