Immunoreactive met-enkephalin plasma concentrations in chronic alcoholics and in children born from alcoholic mothers

S. Govoni, A. Bosio, E. Di Monda, G. Fazzari, P. F. Spano, M. Trabucchi

Research output: Contribution to journalArticlepeer-review

Abstract

Several experimental and clinical observations indicate that ethanol ingestion induces specific neurochemical modifications in the Central Nervous System. In particular, an involvement of endogenous opiates has been suggested in the case of alcohol addiction. In this light, the plasma concentrations of met-enkephalin immunoreactive peptides (ME-IR) have been measured in selected groups of chronic alcoholics and in children whose mothers were ethanol addicts. Both groups revealed a marked reduction of ME-IR plasma concentrations when compared with sex and age matched controls.

Original languageEnglish
Pages (from-to)1581-1586
Number of pages6
JournalLife Sciences
Volume33
Issue number16
DOIs
Publication statusPublished - Oct 17 1983

ASJC Scopus subject areas

  • Pharmacology

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