The available evidence suggests that measurement of the level of total sHLA-1 antigens and of donor-derived and recipient-derived allospecificities as well as the characterization of their variants in recipient's serum may provide useful information to differentiate graft rejections from infections in allograft recipients. Moreover, a significant progress has been made in our understanding of the functional properties of sHLA-I antigens in serum and of their potential role in the modulation of immune responses. If these preliminary results will be confirmed, then sHLA-I antigens are likely to become important reagents to monitor and treat graft recipients.
|Number of pages||4|
|Journal||Archivum Immunologiae et Therapiae Experimentalis|
|Publication status||Published - 1998|
- Graft recipients
- Graft rejections
- Hla soluble molecules
ASJC Scopus subject areas