Immunosuppressive drugs are widely used to treat patients with chronic inflammatory diseases that follow an aggressive course and are resistant to conventional therapies. The immunosuppressive agents more commonly employed in the treatment of children with chronic inflammatory diseases are methotrexate, cyclosporine A, azathioprine, and cyclophosphamide. We review the main characteristics of these drugs and point out their major indications in the treatment of children with chronic rheumatic diseases. The personal experience on the use of pulse intravenous cyclophosphamide in the treatment lupus nephritis will also be presented.
|Translated title of the contribution||Immunosuppressive drugs|
|Number of pages||7|
|Publication status||Published - 2000|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health