Immunotherapy: A new horizon for egg allergy?

Andrea D. Praticò, Gianni Mistrello, Mario La Rosa, Michele Miraglia Del Giudice, Gianluigi Marseglia, Carmelo Salpietro, Salvatore Leonardi

Research output: Contribution to journalArticle


Egg allergy is the second most frequent food allergy in children of the Western Countries, with an overall prevalence of 1-3%. Today strict avoidance diet is the only treatment, but its feasibility is difficult to obtain in childhood because of the large amount of egg proteins present in different foods. From 1998, a growing number of protocols on immunotherapy for egg allergy have been published, but all of them differ for patients' age, inclusion of high-risk patients, amount of allergen administered, duration of the protocols and presence of a control group. We reviewed the protocols performed in the last 15 years, to underline the most important issues in this kind of food immunotherapy, and the rates of tolerance or desensitization induction.

Original languageEnglish
Pages (from-to)677-686
Number of pages10
JournalExpert Review of Clinical Immunology
Issue number5
Publication statusPublished - 2014


  • allergy
  • desensitization
  • egg
  • oral immunotherapy
  • review

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Medicine(all)

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  • Cite this

    Praticò, A. D., Mistrello, G., La Rosa, M., Miraglia Del Giudice, M., Marseglia, G., Salpietro, C., & Leonardi, S. (2014). Immunotherapy: A new horizon for egg allergy? Expert Review of Clinical Immunology, 10(5), 677-686.