Immunotherapy of neuroblastoma: Present, past and future

Lizzia Raffaghello, Vito Pistoia

Research output: Contribution to journalArticlepeer-review

Abstract

Neuroblastoma is a neuroectodermal tumor of childhood with poor prognosis and low survival in patients with advanced-stage disease who respond to conventional therapies but unfortunately, often present relapse. Therefore, the search for novel therapeutic strategies is warranted and represents the objective of many investigators. Among the new, innovative approaches, immunotherapy has attracted much interest. However, until recently, little information was available about the immunogenicity of human neuroblastoma.

Original languageEnglish
Pages (from-to)509-518
Number of pages10
JournalExpert Review of Neurotherapeutics
Volume6
Issue number4
DOIs
Publication statusPublished - Apr 2006

Keywords

  • Dendritic cells
  • Disialoganglioside 2
  • Immunocytokines
  • Immunogenicity
  • Immunotherapy
  • Interleukin-2
  • Natural killer cells
  • Neuroblastoma

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

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