Impact and natural history of postprocedural aortic regurgitation on early and midterm mortality following transcatheter aortic valve implantation in high-risk patients with severe aortic stenosis

Alfonso Ielasi, Azeem Latib, Francesco Maria Sacco, Charis Costopoulos, Filippo Figini, Antonio Grimaldi, Charbel Naim, Francesco Maisano, Alaide Chieffo, Matteo Montorfano, Ottavio Alfieri, Antonio Colombo

Research output: Contribution to journalArticlepeer-review

Abstract

Background Post-procedural aortic regurgitation (AR) negatively impacts the prognosis after trans-catheter aortic valve implantation. However, data evaluating the impact of different post-procedural AR grades (particularly mild) on clinical outcomes are still important. Aim and Methods A retrospective cohort analysis was performed on all consecutive patients with severe aortic stenosis who underwent trans-catheter aortic valve implantation between July 2008 and August 2011 in a single Institution. Aim of the study was to evaluate the impact of different post-procedural AR grades on early and mid-term clinical outcomes. Results 322 consecutive patients were evaluated. At post-procedural echocardiographic evaluation: 105 (32.6%) patients had no AR, 204 (63.4%) mild AR and 13 (4%) moderate/severe AR. In-hospital mortality was higher in patients with moderate/severe AR than in those with absent or mild AR (38.5% vs. 2.6%, P

Original languageEnglish
Pages (from-to)286-295
Number of pages10
JournalJournal of Cardiovascular Medicine
Volume16
Issue number4
DOIs
Publication statusPublished - Apr 4 2015

Keywords

  • aortic regurgitation
  • aortic stenosis
  • transcatheter aortic valve implantation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Impact and natural history of postprocedural aortic regurgitation on early and midterm mortality following transcatheter aortic valve implantation in high-risk patients with severe aortic stenosis'. Together they form a unique fingerprint.

Cite this