Impact of a clinical microbiology-intensive care consulting program in a cardiothoracic intensive care unit

Fabio Arena, Sabino Scolletta, Luca Marchetti, Angelo Galano, Enivarco Maglioni, Tommaso Giani, Elisabetta Corsi, Silvia Lombardi, Bonizella Biagioli, Gian Maria Rossolini

Research output: Contribution to journalArticlepeer-review

Abstract

A preintervention-postintervention study was carried out over a 4-year period to assess the impact of an antimicrobial stewardship intervention, based on clinical microbiologist ward rounds (clinical microbiology-intensive care partnership [CMICP]), at a cardiothoracic intensive care unit. Comparison of clinical data for 37 patients with diagnosis of bacteremia (18 from preintervention period, 19 from postintervention period) revealed that CMICP implementation resulted in (1) significant increase of appropriate empirical treatments (+34%, P =.029), compliance with guidelines (+28%, P =.019), and number of de-escalations (+42%, P =.032); and (2) decrease (average = 2.5 days) in time to optimization of antimicrobial therapy and levofloxacin (Δ 2009-2012 = -74 defined daily dose [DDD]/1,000 bed days) and teicoplanin (Δ 2009-2012 = -28 DDD/1,000 bed days) use.

Original languageEnglish
Pages (from-to)1018-1021
Number of pages4
JournalAJIC: American Journal of Infection Control
Volume43
Issue number9
DOIs
Publication statusPublished - Sep 1 2015

Keywords

  • Antibiotic consumption
  • Antimicrobial stewardship
  • Clinical microbiologist
  • Consultant
  • Intensive care unit
  • Sepsis

ASJC Scopus subject areas

  • Infectious Diseases
  • Public Health, Environmental and Occupational Health
  • Epidemiology
  • Health Policy

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