Impact of advanced age on the outcome of liver resection

Luca Aldrighetti, Marcella Arru, Roberto Caterini, Renato Finazzi, Laura Comotti, Giorgio Torri, Gianfranco Ferla

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

The aim of this retrospective study was to evaluate the influence of age on the outcome of liver resection. A total of 129 consecutive liver resections were divided into two groups: ≥ 70 years old [old group (O-group)] and <70 years old [young group (Y-group)]. The two groups were first compared for the variables potentially affecting the postoperative course, including diagnosis, concomitant diseases, previous abdominal surgery, type of operation (major or minor resection), associated procedures, presence and length of portal clamping, intraoperative blood losses and transfusions, and length of operation. The outcome of liver resections was evaluated in terms of postoperative mortality, morbidity, transfusions, and length of hospitalization. The Y-group included 97 resections in 95 patients, aged 55.9 ± 10.5 years (mean ± SD; range: 23-69 years), and the O-group included 32 resections in 32 patients, aged 73.7 ± 3.2 years (mean ± SD; range: 70-82 years. The O-group included more hepatocellular carcinomas (46.9% versus 20.6%, p = 0.002) and cardiovascular diseases (15.2% versus 1.0%, p = 0.004). The two groups were comparable (p > 0.05) when evaluated for all other listed variables. As regards the postoperative outcome, the length of hospitalization was similar (median, range: 9.5 days, 5-60 days in the Y-group and 9 days, 5-48 days in the O-group) and the need for postoperative transfusions were not statistically different. Mortality included one case among young patients, while no deaths were recorded among elderly patients. Postoperative morbidity was higher in Y-group than in O-group (21.6% versus 9.4%, p = 0.2). In conclusion, the age factor does not negatively affect the outcome of liver resections.

Original languageEnglish
Pages (from-to)1149-1154
Number of pages6
JournalWorld Journal of Surgery
Volume27
Issue number10
DOIs
Publication statusPublished - Oct 1 2003

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Liver
Age Factors
Hospitalization
Retrospective Studies
Morbidity
Mortality

ASJC Scopus subject areas

  • Surgery

Cite this

Aldrighetti, L., Arru, M., Caterini, R., Finazzi, R., Comotti, L., Torri, G., & Ferla, G. (2003). Impact of advanced age on the outcome of liver resection. World Journal of Surgery, 27(10), 1149-1154. https://doi.org/10.1007/s00268-003-7072-y

Impact of advanced age on the outcome of liver resection. / Aldrighetti, Luca; Arru, Marcella; Caterini, Roberto; Finazzi, Renato; Comotti, Laura; Torri, Giorgio; Ferla, Gianfranco.

In: World Journal of Surgery, Vol. 27, No. 10, 01.10.2003, p. 1149-1154.

Research output: Contribution to journalArticle

Aldrighetti, L, Arru, M, Caterini, R, Finazzi, R, Comotti, L, Torri, G & Ferla, G 2003, 'Impact of advanced age on the outcome of liver resection', World Journal of Surgery, vol. 27, no. 10, pp. 1149-1154. https://doi.org/10.1007/s00268-003-7072-y
Aldrighetti L, Arru M, Caterini R, Finazzi R, Comotti L, Torri G et al. Impact of advanced age on the outcome of liver resection. World Journal of Surgery. 2003 Oct 1;27(10):1149-1154. https://doi.org/10.1007/s00268-003-7072-y
Aldrighetti, Luca ; Arru, Marcella ; Caterini, Roberto ; Finazzi, Renato ; Comotti, Laura ; Torri, Giorgio ; Ferla, Gianfranco. / Impact of advanced age on the outcome of liver resection. In: World Journal of Surgery. 2003 ; Vol. 27, No. 10. pp. 1149-1154.
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AB - The aim of this retrospective study was to evaluate the influence of age on the outcome of liver resection. A total of 129 consecutive liver resections were divided into two groups: ≥ 70 years old [old group (O-group)] and <70 years old [young group (Y-group)]. The two groups were first compared for the variables potentially affecting the postoperative course, including diagnosis, concomitant diseases, previous abdominal surgery, type of operation (major or minor resection), associated procedures, presence and length of portal clamping, intraoperative blood losses and transfusions, and length of operation. The outcome of liver resections was evaluated in terms of postoperative mortality, morbidity, transfusions, and length of hospitalization. The Y-group included 97 resections in 95 patients, aged 55.9 ± 10.5 years (mean ± SD; range: 23-69 years), and the O-group included 32 resections in 32 patients, aged 73.7 ± 3.2 years (mean ± SD; range: 70-82 years. The O-group included more hepatocellular carcinomas (46.9% versus 20.6%, p = 0.002) and cardiovascular diseases (15.2% versus 1.0%, p = 0.004). The two groups were comparable (p > 0.05) when evaluated for all other listed variables. As regards the postoperative outcome, the length of hospitalization was similar (median, range: 9.5 days, 5-60 days in the Y-group and 9 days, 5-48 days in the O-group) and the need for postoperative transfusions were not statistically different. Mortality included one case among young patients, while no deaths were recorded among elderly patients. Postoperative morbidity was higher in Y-group than in O-group (21.6% versus 9.4%, p = 0.2). In conclusion, the age factor does not negatively affect the outcome of liver resections.

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